Natera genetic testing reviews: Learn all about its tests, accuracy, and pricing

For many, genetic testing is about exploring inherited traits, discovering ancestry, or assessing health risks. Natera elevates DNA analysis by focusing on advanced applications in cancer diagnostics, organ transplantation, and reproductive health. 

The company uses cell-free DNA (cfDNA) to introduce personalized genetics into everyday healthcare, helping detect issues early and allowing for targeted treatments. 

Our Natera genetic testing review will present key features, helping you understand how Natera’s tests work and whether they’re the right solution for you. We’ll cover data security, pricing, and user reviews to give you a complete picture of this service.

Natera genetic testing: An overview

Natera is a genetic testing company based in Austin, Texas, with a lab in San Carlos, California. The company specializes in cfDNA testing, a non-invasive method that analyzes DNA fragments in the blood to screen for genetic conditions. This technology is known for its high accuracy in detecting Down syndrome and other genetic disorders. 

The company specializes in organ health, oncology, and women’s health. Natera’s focus on these niches makes it a go-to option for individuals seeking targeted insights. Its genetic tests are designed to:

• Detect genetic risks during pregnancy through non-invasive prenatal testing (NIPT)

• Assess the risk of organ transplant rejection

• Identify hereditary cancer markers

• Help address fertility concerns

• Determine the baby’s gender

Natera has also contributed to over 250 peer-reviewed publications and serves millions of patients worldwide. 

How Natera genetic testing works

Source: Natera

Natera can provide meaningful health information through its easy and non-invasive three-step testing process: 

1. Test: You start by giving a small sample of blood or saliva. You can schedule a blood draw at a partner lab or opt for the convenience of an at-home collection.

2. Know: Once your sample reaches the lab, the experts assess unique DNA markers related to various aspects of your health. The results, accessible via an online patient portal, will help you identify health risks, monitor treatment progress, or detect issues early. 

3. Decide: With this information, you can work with your doctor to make informed decisions regarding your health.

Natera reviews: Breaking down six crucial aspects

To evaluate the value of Natera genetic testing, we've analyzed the company’s services based on six essential criteria: 

1. Types of insights

2. Results interpretation

3. Quality and accuracy of results

4. Pricing and payment options

5. Privacy and data security

6. Customer experiences and reviews

1. Types of insights

Natera’s DNA tests provide valuable insight into specialized areas like prenatal care, cancer detection, and reproductive health.

The table below highlights the key testing categories:

| Test       | Category       | Purpose                                                                                    |
|------------|--------------|--------------------------------------------------------------------------------------------|
| Signatera™ | Cancer Testing | Monitors cancer by detecting ctDNA. Helps spot recurrence earlier than traditional methods |
| Altera™    | Cancer Testing | Profiles tumors to guide treatment based on genetic details                                |
| Empower™   | Cancer Testing | Screens for inherited cancer risks in families (covers 12+ types of cancer)                |
| Panorama™  | Women’s Health | A prenatal test to check for common genetic conditions like Down syndrome in a fetus       |
| Horizon™   | Women’s Health | Screens parents for genes that could lead to serious inherited conditions in children      |
| Spectrum™  | Women’s Health | Identifies the healthiest embryos during IVF to improve pregnancy success                  |
| Vistara™   | Women’s Health | Checks for extra genetic conditions in a baby that regular tests might miss                |
| Anora™     | Women’s Health | Examines miscarriages to find genetic causes and help families plan future pregnancies     |
| Prospera™  | Organ Health   | Assesses transplant rejection risks                                                        |
| Renasight™ | Organ Health   | Tests for 380+ genes related to hereditary kidney diseases

Still, the focus on these niches limits the broader information some users may seek. Natera’s tests do not offer comprehensive whole-genome analysis and wellness-related insights, such as nutrition and fitness health, which limits its usefulness for the general public.

2. Results interpretation

Natera's genetic tests assess risk levels for various conditions, providing well-presented reports. Still, due to the complexity of the results, it is advisable to book a consultation with a genetic counselor.

Results from reproductive tests are categorized as “Low Risk” or “High Risk,” indicating the likelihood of certain genetic conditions in a baby.

In oncology, Natera's Signature test determines whether tumor DNA is present in the blood, helping identify potential cancer risks. The company provides genetic counseling to help patients understand their results and navigate the next steps.

While Natera's genomic tests offer valuable insights, its NIPT, organ health, and cancer screenings focus on specific markers and cannot detect all genetic conditions. 

Pro tip: If you're seeking insights into all aspects of your physical and mental health, a test that analyzes your entire genome might be a better fit. Nucleus uses whole-genome sequencing to analyze nearly 100% of your genome, identifying rare genetic markers linked to chronic diseases and providing comprehensive reports on hundreds of health conditions.

3. Quality and accuracy of results

Natera DNA tests are performed in ISO 13485-certified and CAP-accredited labs. These labs use advanced technologies, such as cell-free DNA analysis, to detect genetic material from fetal, tumor, or donor organ cells with a blood draw.

Over 100 peer-reviewed studies back these tests. For example, Panorama™ non-invasive prenatal test is highly effective at detecting Down syndrome in pregnancies and has a low rate of false positives. Natera’s oncology tests are similarly well-supported by clinical research and offer valuable insights into the presence of malignant DNA in the body. This allows doctors to spot relapse early, track how well the treatment is going, and adjust therapy. 

Even though Natera's tests are highly accurate, some users have encountered issues, such as inconclusive results, as outlined by this Reddit user: 

[Reddit](https://www.reddit.com/r/NIPT/comments/10sdc43/natera_panorama_inconclusive_due_to_low_fetal/)

The Signature test, which tracks cancer, is very sensitive but not flawless. Its negative result doesn't always mean cancer is gone, and it doesn't guarantee it won't return, which is why it's vital to review your results with a doctor.

Bonus read: Discover how Natera compares to Invitae in our Natera vs. Invitae review. 

4. Pricing and payment options

Natera does not clearly state its prices. Costs vary depending on the complexity of the test and the patient's insurance plan. Patients can use the Test Cost Estimator available on Natera's website to understand potential charges or contact billing experts for personalized estimates.

Natera accepts payment through all insurance plans, including Medicare. Since the company is an in-network provider with many national and regional healthcare plans, patients frequently benefit from lower out-of-pocket costs.

For those needing additional financial support, Natera offers programs to make testing more affordable:

• Discounted cash rates lower costs for out-of-pocket payments.

• Compassionate care offers financial support for patients facing hardships (should be eligible).

• Interest-free payment plans start at just $25 per month.

If patients are billed for co-pay or co-insurance, Natera provides information about its financial assistance programs to help manage costs.

Despite these options, Natera has faced criticism for its pricing and billing practices. Check out the details in the following table:

| Concern                          | Potential issues                                                                            |
|----------------------------------|-------------------------------------------------------------------------------------------|
| High out-of-pocket costs         | Even with insurance, patients receive large bills exceeding the initially quoted price.     |
| Complex billing practices        | Customers often struggle to determine how billing and insurance are applied.                |
| Overcharging insurance companies | Reports suggest Natera bills insurers higher amounts, leading to increased patient co-pays. |
| Lack of transparency             | Natera does not always provide clear, upfront information about potential costs

[Reddit](https://www.reddit.com/r/BabyBumps/comments/18615di/comment/kb5qgw2/?utm_source=share&utm_medium=web3x&utm_name=web3xcss&utm_term=1&utm_content=share_button/)

5. Privacy and data security

Source: Natera

Natera takes data privacy seriously and complies with HIPAA regulations to protect personal and genetic information.

According to its policies, Natera safeguards data against unauthorized access, alteration, or disclosure. The samples are securely stored and disposed of following strict protocols.

Natera employs several measures to ensure the security of customers' data:

• TLS encryption

• SOC 2 compliance

• NIST standards

• PCI-DSS compliance

If you are a Natera user, you can control how your data is used and choose to delete it whenever you wish.

6. Customer experiences and reviews

Natera has received mixed customer feedback, with many users sharing concerns about their experiences. 

Some customers have reported receiving bills significantly higher than expected. For example, one Reddit user was allegedly quoted a specific amount by Natera representatives for prenatal genetic testing, only to receive bills that were substantially higher, exceeding $1,000: 

[Reddit](https://www.reddit.com/r/NewParents/comments/yqm2q9/word_of_caution_natera_predatory_pricing_practices/?utm_source=share&utm_medium=web3x&utm_name=web3xcss&utm_term=1&utm_content=share_button)

Additionally, there are concerns regarding the accuracy of prenatal tests. Some users have reported false positive results, leading to unnecessary stress for expecting parents. One Reddit user recounted receiving a false positive on the Panorama test, which caused significant anxiety until further testing confirmed the baby was healthy:

[Reddit](https://www.reddit.com/r/NIPT/comments/15wv80d/false_positive_on_natera_test_myriad_results_are/?utm_source=share&utm_medium=web3x&utm_name=web3xcss&utm_term=1&utm_content=share_button)

These issues have led to legal actions against Natera. In 2021, the company faced class action lawsuits alleging deceptive billing practices after Natera charged patients significantly more than the advertised price for genetic tests.

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How accurate is Natera's gender test?

The Natera Panorama™ test claims to determine a baby's gender as early as nine weeks into pregnancy by analyzing fetal DNA in the mother's blood. While the test is marketed as having over 99% accuracy for gender determination, its reliability has come under scrutiny in recent years.

There have been multiple class-action lawsuits against Natera, with some parents claiming the test provided incorrect results. Genetic gender test errors might occur if there is not enough fetal DNA in the mother’s blood, especially if the test is done too early in pregnancy. However, when one takes the test after week 10 of gestation, the test is about 99% reliable. 

While the test offers convenience and early gender determination, users should understand its limitations and consult healthcare providers to confirm results before making important decisions.

Final thoughts: Is Natera the best fit for you?

Natera's specialized genetic tests are problem-specific and a good starting point for anyone seeking targeted health information. These tests are reliable and well-suited for addressing particular health concerns.

For individuals aiming to optimize their health, diet, fitness, and overall well-being or to prevent diseases through actionable recommendations, a more extensive analysis like whole genome sequencing (WGS) could be beneficial. WGS examines your complete DNA, offering insights that can guide personalized health strategies and disease prevention measures. 

One such option is Nucleus’ DNA test, which offers whole genome sequencing and a complete genetic analysis with high accuracy. It analyzes nearly 100% of your genome, your unique lifestyle, and environmental factors to provide tailored recommendations to optimize your well-being. It also identifies specific genetic markers for common and rare conditions such as heart disease, Alzheimer's, and hereditary cancers. 

Nucleus: Get personalized health insights through whole-genome sequencing (WGS)

Nucleus is a DNA platform that offers an at-home testing kit based on whole-genome sequencing technology. Unlike genotyping tests that look at only 0.01% of your DNA, Nucleus analyzes almost 100% of your genome with 99.9% accuracy, providing detailed insights and uncovering rare genetic variants that could impact your health.

While physician-approved whole-genome tests can cost thousands of dollars, Nucleus offers its premium service for only $399. The price includes the test kit, two-way shipping, and access to over 800 health and trait reports, making it an affordable and accessible option.

Nucleus also sends you updated reports when new genetic research emerges to ensure your data remains relevant.

[X](https://twitter.com/nikofotos/status/1782780325967302970)

Your Nucleus report includes clear, actionable information about your genetic predispositions, including risks for life-altering health conditions, such as: 

• Heart disease

• Cancer

• Neurological conditions

• Mental health issues

• Dietary responses and food intolerances

• Energy levels and focus

Your Nucleus report also explores 9+ personal traits, including BMI, height, intelligence, muscle strength, and male-pattern baldness.

Nucleus’ test results are easy to understand. The platform uses advanced data visualizations to present your results clearly so anyone can comprehend complex genetic data. If you need additional support or advice, Nucleus partners with SteadyMD, offering diagnostic guidance from board-certified counselors for you and your family.

Getting started with Nucleus

Embarking on your personalized health journey with Nucleus is straightforward:

1. Sign up for Nucleus Premium

2. Provide your personal information 

3. Place the order 

The test has a cheek swab for easy at-home DNA collection. After collecting your sample, use the prepaid package to return it to the lab. You can check your results in your Nucleus online account in 6–8 weeks.

Nucleus is a fully regulated, HIPAA-compliant platform that partners exclusively with certified U.S. labs. Your data and samples are handled securely to ensure accuracy, privacy, and reliability.

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|------------------------------------------------------------------------------------|-----------------------------------------------------------------------------|
| [Myriad Genetics review](https://mynucleus.com/blog/myriad-genetics-review)        | [tellmeGen review](https://mynucleus.com/blog/tellmegen-review)             |
| [My Heritage review](https://mynucleus.com/blog/myheritage-review)                 | [Sequencing.com review](https://mynucleus.com/blog/sequencingcom-review)    |
| [Rupa Health review](https://mynucleus.com/blog/rupa-health-review)                | [InsideTracker review](https://mynucleus.com/blog/insidetracker-review)     |
| [23andMe alternatives](https://mynucleus.com/blog/23andme-alternatives)            | [Nebula Genomics review](https://mynucleus.com/blog/nebula-genomics-review) |
| [InsideTracker alternatives](https://mynucleus.com/blog/insidetracker-alternative) | [Invitae review](https://mynucleus.com/blog/invitae-genetic-testing-review) |
| [SelfDecode review](https://mynucleus.com/blog/selfdecode-review)                  |                                                                             |

Featured image source: National Cancer Institute