the science
A deeper look into your DNA
Nucleus’ state-of-the-art testing and analysis unlock previously unavailable insights about how your DNA influences your health and longevity.
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Physician-ordered test
Physician-ordered test
troubleshoot
30x sequencing depth
30x sequencing depth
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Sequenced in the U.S.
Sequenced in the U.S.
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HIPAA compliant
HIPAA compliant
verified
CLIA certified
CLIA certified
biotech
CAP accredited
CAP accredited
our technology
A new standard in consumer DNA testing
1,000x
more DNA sequenced with Nucleus*
*compared to 23andMe, Ancestry, and similar tests
100% of your DNA
Less than 0.1% of your DNA
Less than 0.1% of your DNA
our technology
A new standard in consumer DNA testing
1,000x
more DNA sequenced with Nucleus*
*compared to 23andMe, Ancestry, and similar tests
100% of your DNA
0.1% of your DNA
0.1% of your DNA
our technology
A new standard in consumer DNA testing
1,000x
more DNA sequenced with Nucleus*
*compared to 23andMe, Ancestry, and similar tests
100%
0.1%
01 Research
Peer-reviewed research
We build upon leading private, public, and academic research to provide the most comprehensive analysis.
02 Testing
Whole-genome sequencing
Our whole-genome test is powered by Illumina's cutting-edge Novaseq X Sequencing System.
30x
Sequencing depth
30x
Sequencing depth
Quality testing
We perform 30x whole-genome sequencing to provide clinical-grade results.
Built by world-class collaborators
Our team brings decades of combined experience across genomics, computational biology, and database security. We're driven by the shared belief that we all deserve to be as informed as possible about our own health.
Lasse Folkersen, Ph.D.
Formerly lead scientist at the Danish National Genome Center and author of 100+ peer-reviewed publications
Pioneer of the largest open-source genetic analysis site
Barry Starr, Ph.D.
Formerly director of outreach at the Stanford Department of Genetics and director of science communications at Ancestry Health
Robert Plomin, Ph.D.
Professor at King’s College London and one of the most well-cited behavioral geneticists in history
Margit Burmeister, Ph.D.
Professor at the University of Michigan Medical School
Jerry Lanchbury, Ph.D.
Former Chief Scientific Officer at Myriad Genetics
"We intentionally designed Nucleus to deliver the highest quality clinical genetic tests, in a consumer product that's accessible to nearly everyone."
Lasse Folkersen, Ph.D.
Chief Scientific Officer
Go deeper
How accurate is Nucleus?
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Our whole-genome DNA sequencing is more than 99.9% accurate. From research to testing, we go above and beyond industry standards to bring you safe and accurate results.
While your DNA doesn’t change (it’s yours for life!), your Nucleus results can. Genetic research is always improving, so we constantly update your health results to give you the most accurate read on your health.
How accurate is Nucleus?
add
Our whole-genome DNA sequencing is more than 99.9% accurate. From research to testing, we go above and beyond industry standards to bring you safe and accurate results.
While your DNA doesn’t change (it’s yours for life!), your Nucleus results can. Genetic research is always improving, so we constantly update your health results to give you the most accurate read on your health.
How accurate is Nucleus?
add
Our whole-genome DNA sequencing is more than 99.9% accurate. From research to testing, we go above and beyond industry standards to bring you safe and accurate results.
While your DNA doesn’t change (it’s yours for life!), your Nucleus results can. Genetic research is always improving, so we constantly update your health results to give you the most accurate read on your health.
What genes does Nucleus report on?
add
Nucleus’ whole-genome test currently analyzes thousands of genes to provide PRSs (polygenic risk scores) for 20+ common-complex diseases. We also identify pathogenic or likely pathogenic variants that increase risk for 900+ rare genetic diseases that could affect you or your children. See full list
What genes does Nucleus report on?
add
Nucleus’ whole-genome test currently analyzes thousands of genes to provide PRSs (polygenic risk scores) for 20+ common-complex diseases. We also identify pathogenic or likely pathogenic variants that increase risk for 900+ rare genetic diseases that could affect you or your children. See full list
What genes does Nucleus report on?
add
Nucleus’ whole-genome test currently analyzes thousands of genes to provide PRSs (polygenic risk scores) for 20+ common-complex diseases. We also identify pathogenic or likely pathogenic variants that increase risk for 900+ rare genetic diseases that could affect you or your children. See full list
How does Nucleus analyze DNA?
add
Nucleus uses whole-genome sequencing to analyze your DNA for millions of variants that can impact your risk for diseases. Nucleus classifies variants into three major categories: Causal, high-effect, and common.
Causal variants can single-handedly cause a disease or trait but are extremely rare.
High-effect variants have a strong effect on diseases and traits — just one of them can sometimes be enough to substantially increase your chances of developing diseases or having a trait.
Common variants are DNA differences more commonly found in people. One common variant alone may not significantly influence your risk of developing a specific disease or your chance of having a certain trait. But, collectively, these variants can shape your traits and influence your disease risks. The combined impact of these variants are measured through our innovative algorithms called common genetic scores (also known as polygenic scores).
Through our whole-genome analysis, we are able to identify these variants and provide insights into how they affect your health and well-being.
How does Nucleus analyze DNA?
add
Nucleus uses whole-genome sequencing to analyze your DNA for millions of variants that can impact your risk for diseases. Nucleus classifies variants into three major categories: Causal, high-effect, and common.
Causal variants can single-handedly cause a disease or trait but are extremely rare.
High-effect variants have a strong effect on diseases and traits — just one of them can sometimes be enough to substantially increase your chances of developing diseases or having a trait.
Common variants are DNA differences more commonly found in people. One common variant alone may not significantly influence your risk of developing a specific disease or your chance of having a certain trait. But, collectively, these variants can shape your traits and influence your disease risks. The combined impact of these variants are measured through our innovative algorithms called common genetic scores (also known as polygenic scores).
Through our whole-genome analysis, we are able to identify these variants and provide insights into how they affect your health and well-being.
How does Nucleus analyze DNA?
add
Nucleus uses whole-genome sequencing to analyze your DNA for millions of variants that can impact your risk for diseases. Nucleus classifies variants into three major categories: Causal, high-effect, and common.
Causal variants can single-handedly cause a disease or trait but are extremely rare.
High-effect variants have a strong effect on diseases and traits — just one of them can sometimes be enough to substantially increase your chances of developing diseases or having a trait.
Common variants are DNA differences more commonly found in people. One common variant alone may not significantly influence your risk of developing a specific disease or your chance of having a certain trait. But, collectively, these variants can shape your traits and influence your disease risks. The combined impact of these variants are measured through our innovative algorithms called common genetic scores (also known as polygenic scores).
Through our whole-genome analysis, we are able to identify these variants and provide insights into how they affect your health and well-being.
What is whole-genome sequencing?
add
Most consumer genetic tests use a technology called microarray testing. Microarray tests look at only a tiny fraction of your DNA — less than 0.1%. This means that important health insights can be missed. In comparison, Nucleus looks at closer to 100% of your DNA — 1,000x more DNA than microarray tests — to give you a more complete picture of your health risks. Nucleus performs 30x high-depth whole-genome sequencing coverage.
What is whole-genome sequencing?
add
Most consumer genetic tests use a technology called microarray testing. Microarray tests look at only a tiny fraction of your DNA — less than 0.1%. This means that important health insights can be missed. In comparison, Nucleus looks at closer to 100% of your DNA — 1,000x more DNA than microarray tests — to give you a more complete picture of your health risks. Nucleus performs 30x high-depth whole-genome sequencing coverage.
What is whole-genome sequencing?
add
Most consumer genetic tests use a technology called microarray testing. Microarray tests look at only a tiny fraction of your DNA — less than 0.1%. This means that important health insights can be missed. In comparison, Nucleus looks at closer to 100% of your DNA — 1,000x more DNA than microarray tests — to give you a more complete picture of your health risks. Nucleus performs 30x high-depth whole-genome sequencing coverage.
Where does Nucleus sequence DNA?
add
Nucleus is proud to sequence all DNA samples 100% in the United States. DNA samples are never sent or stored overseas.
Where does Nucleus sequence DNA?
add
Nucleus is proud to sequence all DNA samples 100% in the United States. DNA samples are never sent or stored overseas.
Where does Nucleus sequence DNA?
add
Nucleus is proud to sequence all DNA samples 100% in the United States. DNA samples are never sent or stored overseas.
How secure and private is Nucleus?
add
Your privacy is our highest priority. In addition to being HIPAA-compliant, CLIA-certified, and CAP-accredited, we require all of our users to sign in with 2-factor authentication to ensure the security of your DNA sample, your DNA test results, and other personal data you provide to us.
Your cheek DNA sample will be safely destroyed within 60 days of being received by the lab.
You own your DNA data. You can download your DNA file(s) at any time. We do not share your DNA or health data with third parties, except as legally required or with your explicit consent.
How secure and private is Nucleus?
add
Your privacy is our highest priority. In addition to being HIPAA-compliant, CLIA-certified, and CAP-accredited, we require all of our users to sign in with 2-factor authentication to ensure the security of your DNA sample, your DNA test results, and other personal data you provide to us.
Your cheek DNA sample will be safely destroyed within 60 days of being received by the lab.
You own your DNA data. You can download your DNA file(s) at any time. We do not share your DNA or health data with third parties, except as legally required or with your explicit consent.
How secure and private is Nucleus?
add
Your privacy is our highest priority. In addition to being HIPAA-compliant, CLIA-certified, and CAP-accredited, we require all of our users to sign in with 2-factor authentication to ensure the security of your DNA sample, your DNA test results, and other personal data you provide to us.
Your cheek DNA sample will be safely destroyed within 60 days of being received by the lab.
You own your DNA data. You can download your DNA file(s) at any time. We do not share your DNA or health data with third parties, except as legally required or with your explicit consent.
Is Nucleus regulated?
add
Yes. Nucleus is a medical laboratory that follows strict clinical regulations for genetic testing. We are HIPAA-compliant, CLIA-certified, and CAP-accredited, meaning we adhere to rigorous clinical guidelines and are legally required to protect your protected health information (PHI).
Is Nucleus regulated?
add
Yes. Nucleus is a medical laboratory that follows strict clinical regulations for genetic testing. We are HIPAA-compliant, CLIA-certified, and CAP-accredited, meaning we adhere to rigorous clinical guidelines and are legally required to protect your protected health information (PHI).
Is Nucleus regulated?
add
Yes. Nucleus is a medical laboratory that follows strict clinical regulations for genetic testing. We are HIPAA-compliant, CLIA-certified, and CAP-accredited, meaning we adhere to rigorous clinical guidelines and are legally required to protect your protected health information (PHI).
Contact support
Contact support
Contact support
In the news
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Take the first step today
Test from the comfort of your home. No doctor’s office. No hassle.
Take the first step today
Test from the comfort of your home. No doctor’s office. No hassle.
Buy your kit
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HIPAA-COMPLIANT
CLIA-CERTIFIED
CAP-accredited
Made in the U.S.A.
@ 2024 Nucleus Genomics, Inc.
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@ 2024 Nucleus Genomics, Inc.
HIPAA-COMPLIANT
CLIA-CERTIFIED
CAP-accredited
Made in the U.S.A.
Learn
HIPAA-COMPLIANT
CLIA-CERTIFIED
CAP-accredited
Made in the U.S.A.
@ 2024 Nucleus Genomics, Inc.