FAQ
Frequently asked
Frequently asked
What will my results tell me?
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Your Nucleus results include personalized insights about how your unique DNA combines with your lifestyle factors to influence your disease risks and trait dispositions. Nucleus currently provides reports for the following diseases: ADHD Age-related macular degeneration (AMD) Alcohol dependence Alzheimer's disease Anxiety disorders Asthma Bipolar disorder Celiac disease Chronic pain Colorectal cancer Coronary artery disease Depression Endometriosis Female breast cancer Gastric cancer Hypertension Insomnia Male breast cancer Migraine Multiple sclerosis OCD Osteoarthritis Ovarian cancer Parkinson's disease Polycystic ovarian syndrome (PCOS) Prostate cancer Restless legs syndrome Rheumatoid arthritis Schizophrenia Type 2 diabetes Nucleus currently provides reports for the following traits: BMI Height IQ Left-Handedness Longevity Male-pattern baldness Muscle strength Risk-Taking Seasonal Allergies Severe Acne
What will my results tell me?
add
Your Nucleus results include personalized insights about how your unique DNA combines with your lifestyle factors to influence your disease risks and trait dispositions. Nucleus currently provides reports for the following diseases: ADHD Age-related macular degeneration (AMD) Alcohol dependence Alzheimer's disease Anxiety disorders Asthma Bipolar disorder Celiac disease Chronic pain Colorectal cancer Coronary artery disease Depression Endometriosis Female breast cancer Gastric cancer Hypertension Insomnia Male breast cancer Migraine Multiple sclerosis OCD Osteoarthritis Ovarian cancer Parkinson's disease Polycystic ovarian syndrome (PCOS) Prostate cancer Restless legs syndrome Rheumatoid arthritis Schizophrenia Type 2 diabetes Nucleus currently provides reports for the following traits: BMI Height IQ Left-Handedness Longevity Male-pattern baldness Muscle strength Risk-Taking Seasonal Allergies Severe Acne
What will my results tell me?
add
Your Nucleus results include personalized insights about how your unique DNA combines with your lifestyle factors to influence your disease risks and trait dispositions. Nucleus currently provides reports for the following diseases: ADHD Age-related macular degeneration (AMD) Alcohol dependence Alzheimer's disease Anxiety disorders Asthma Bipolar disorder Celiac disease Chronic pain Colorectal cancer Coronary artery disease Depression Endometriosis Female breast cancer Gastric cancer Hypertension Insomnia Male breast cancer Migraine Multiple sclerosis OCD Osteoarthritis Ovarian cancer Parkinson's disease Polycystic ovarian syndrome (PCOS) Prostate cancer Restless legs syndrome Rheumatoid arthritis Schizophrenia Type 2 diabetes Nucleus currently provides reports for the following traits: BMI Height IQ Left-Handedness Longevity Male-pattern baldness Muscle strength Risk-Taking Seasonal Allergies Severe Acne
How is Nucleus different from 23andMe?
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Most consumer genetic tests use a technology called microarray testing, which often looks at less than 0.1% of your DNA. This means that important health insights can be missed. In comparison, Nucleus looks at close to 100% of your DNA by using a more advanced technology called whole-genome sequencing. By analyzing 1000x more DNA than other tests, Nucleus provides deeper and better insights, giving you a more complete picture of your health risks. In addition, Nucleus incorporates your non-genetic health information, like your blood pressure, cholesterol level, BMI, and more, to identify important health insights that other tests miss.
How is Nucleus different from 23andMe?
add
Most consumer genetic tests use a technology called microarray testing, which often looks at less than 0.1% of your DNA. This means that important health insights can be missed. In comparison, Nucleus looks at close to 100% of your DNA by using a more advanced technology called whole-genome sequencing. By analyzing 1000x more DNA than other tests, Nucleus provides deeper and better insights, giving you a more complete picture of your health risks. In addition, Nucleus incorporates your non-genetic health information, like your blood pressure, cholesterol level, BMI, and more, to identify important health insights that other tests miss.
How is Nucleus different from 23andMe?
add
Most consumer genetic tests use a technology called microarray testing, which often looks at less than 0.1% of your DNA. This means that important health insights can be missed. In comparison, Nucleus looks at close to 100% of your DNA by using a more advanced technology called whole-genome sequencing. By analyzing 1000x more DNA than other tests, Nucleus provides deeper and better insights, giving you a more complete picture of your health risks. In addition, Nucleus incorporates your non-genetic health information, like your blood pressure, cholesterol level, BMI, and more, to identify important health insights that other tests miss.
How accurate is Nucleus?
add
Nucleus’ whole-genome DNA analysis is more than 99.9% accurate. As a clinical-grade test, Nucleus is held to the highest standards to ensure the quality of your DNA analysis.
How accurate is Nucleus?
add
Nucleus’ whole-genome DNA analysis is more than 99.9% accurate. As a clinical-grade test, Nucleus is held to the highest standards to ensure the quality of your DNA analysis.
How accurate is Nucleus?
add
Nucleus’ whole-genome DNA analysis is more than 99.9% accurate. As a clinical-grade test, Nucleus is held to the highest standards to ensure the quality of your DNA analysis.
How long does it take to get my results?
add
Once you complete sign-up, you will receive your Nucleus DNA kit in around 5 business days. After collecting your DNA sample — a simple swab of your cheek — you can ship your sample to the lab for processing using the prepaid shipping envelope included with your kit. Once your sample is received by the laboratory, you can expect your results within 6-8 weeks. You will receive an email once your results are ready to view.
How long does it take to get my results?
add
Once you complete sign-up, you will receive your Nucleus DNA kit in around 5 business days. After collecting your DNA sample — a simple swab of your cheek — you can ship your sample to the lab for processing using the prepaid shipping envelope included with your kit. Once your sample is received by the laboratory, you can expect your results within 6-8 weeks. You will receive an email once your results are ready to view.
How long does it take to get my results?
add
Once you complete sign-up, you will receive your Nucleus DNA kit in around 5 business days. After collecting your DNA sample — a simple swab of your cheek — you can ship your sample to the lab for processing using the prepaid shipping envelope included with your kit. Once your sample is received by the laboratory, you can expect your results within 6-8 weeks. You will receive an email once your results are ready to view.
How does Nucleus analyze my DNA?
add
Nucleus uses whole-genome sequencing to analyze your DNA for millions of variants that can impact your risk for diseases. Nucleus classifies variants into three major categories: Causal, high-effect, and common. Causal variants can single-handedly cause a disease or trait but are extremely rare. High-effect variants have a strong effect on diseases and traits — just one of them can sometimes be enough to substantially increase your chances of developing diseases or having a trait. Common variants are DNA differences more commonly found in people. One common variant alone may not significantly influence your risk of developing a specific disease or your chance of having a certain trait. But, collectively, these variants can shape your traits and influence your disease risks. The combined impact of these variants are measured through our innovative algorithms called common genetic scores (also known as polygenic scores). Through our whole-genome analysis, we are able to identify these variants and provide insights into how they affect your health and well-being.
How does Nucleus analyze my DNA?
add
Nucleus uses whole-genome sequencing to analyze your DNA for millions of variants that can impact your risk for diseases. Nucleus classifies variants into three major categories: Causal, high-effect, and common. Causal variants can single-handedly cause a disease or trait but are extremely rare. High-effect variants have a strong effect on diseases and traits — just one of them can sometimes be enough to substantially increase your chances of developing diseases or having a trait. Common variants are DNA differences more commonly found in people. One common variant alone may not significantly influence your risk of developing a specific disease or your chance of having a certain trait. But, collectively, these variants can shape your traits and influence your disease risks. The combined impact of these variants are measured through our innovative algorithms called common genetic scores (also known as polygenic scores). Through our whole-genome analysis, we are able to identify these variants and provide insights into how they affect your health and well-being.
How does Nucleus analyze my DNA?
add
Nucleus uses whole-genome sequencing to analyze your DNA for millions of variants that can impact your risk for diseases. Nucleus classifies variants into three major categories: Causal, high-effect, and common. Causal variants can single-handedly cause a disease or trait but are extremely rare. High-effect variants have a strong effect on diseases and traits — just one of them can sometimes be enough to substantially increase your chances of developing diseases or having a trait. Common variants are DNA differences more commonly found in people. One common variant alone may not significantly influence your risk of developing a specific disease or your chance of having a certain trait. But, collectively, these variants can shape your traits and influence your disease risks. The combined impact of these variants are measured through our innovative algorithms called common genetic scores (also known as polygenic scores). Through our whole-genome analysis, we are able to identify these variants and provide insights into how they affect your health and well-being.
Can I download my whole-genome file?
add
Yes. You can download your raw whole-genome DNA files (FASTQ or VCF) from the Nucleus website at any time. Upon request, you’ll receive an email with your DNA file(s).
Can I download my whole-genome file?
add
Yes. You can download your raw whole-genome DNA files (FASTQ or VCF) from the Nucleus website at any time. Upon request, you’ll receive an email with your DNA file(s).
Can I download my whole-genome file?
add
Yes. You can download your raw whole-genome DNA files (FASTQ or VCF) from the Nucleus website at any time. Upon request, you’ll receive an email with your DNA file(s).
Is Nucleus covered by my insurance?
add
No, we do not currently accept insurance.
Is Nucleus covered by my insurance?
add
No, we do not currently accept insurance.
Is Nucleus covered by my insurance?
add
No, we do not currently accept insurance.
Testing
Testing
How do I collect my DNA sample?
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Nucleus’ whole-genome test is a simple cheek swab that you can do from the comfort of your own home. Swabbing your cheek is quick and easy — people usually complete it in several minutes.
How do I collect my DNA sample?
add
Nucleus’ whole-genome test is a simple cheek swab that you can do from the comfort of your own home. Swabbing your cheek is quick and easy — people usually complete it in several minutes.
How do I collect my DNA sample?
add
Nucleus’ whole-genome test is a simple cheek swab that you can do from the comfort of your own home. Swabbing your cheek is quick and easy — people usually complete it in several minutes.
How long will it take for my kit to arrive?
add
Once you complete sign-up, you will receive your Nucleus DNA kit in the mail in about 5 business days. You will receive an email notifying you when your kit arrives.
How long will it take for my kit to arrive?
add
Once you complete sign-up, you will receive your Nucleus DNA kit in the mail in about 5 business days. You will receive an email notifying you when your kit arrives.
How long will it take for my kit to arrive?
add
Once you complete sign-up, you will receive your Nucleus DNA kit in the mail in about 5 business days. You will receive an email notifying you when your kit arrives.
What will my Nucleus DNA kit include?
add
Your Nucleus DNA kit includes full instructions, two cheek swabs, a collection tube, and a prepaid return envelope (so you don’t have to pay to send your DNA sample to the lab).
What will my Nucleus DNA kit include?
add
Your Nucleus DNA kit includes full instructions, two cheek swabs, a collection tube, and a prepaid return envelope (so you don’t have to pay to send your DNA sample to the lab).
What will my Nucleus DNA kit include?
add
Your Nucleus DNA kit includes full instructions, two cheek swabs, a collection tube, and a prepaid return envelope (so you don’t have to pay to send your DNA sample to the lab).
Is Nucleus available in New York?
add
No. Due to state regulations, Nucleus is not currently available in New York State.
Is Nucleus available in New York?
add
No. Due to state regulations, Nucleus is not currently available in New York State.
Is Nucleus available in New York?
add
No. Due to state regulations, Nucleus is not currently available in New York State.
Is Nucleus available internationally?
add
No. Nucleus is only available in the U.S. at this time.
Is Nucleus available internationally?
add
No. Nucleus is only available in the U.S. at this time.
Is Nucleus available internationally?
add
No. Nucleus is only available in the U.S. at this time.
Your results
Your results
How long does it take to get my results?
add
Once your sample is received by the laboratory, you can expect your results within 6-8 weeks. You will receive an email once your results are ready to view.
How long does it take to get my results?
add
Once your sample is received by the laboratory, you can expect your results within 6-8 weeks. You will receive an email once your results are ready to view.
How long does it take to get my results?
add
Once your sample is received by the laboratory, you can expect your results within 6-8 weeks. You will receive an email once your results are ready to view.
What will my results tell me?
add
Your Nucleus results include personalized insights about how your unique DNA combines with your lifestyle factors to influence your disease risks and trait dispositions. Nucleus currently provides reports for the following diseases: ADHD Age-related macular degeneration (AMD) Alcohol dependence Alzheimer's disease Anxiety disorders Asthma Bipolar disorder Celiac disease Colorectal cancer Coronary artery disease Depression Female breast cancer Gastric cancer Hypertension Insomnia Male breast cancer Migraine Multiple sclerosis OCD Parkinson's disease Prostate cancer Rheumatoid arthritis Schizophrenia Type 2 diabetes
What will my results tell me?
add
Your Nucleus results include personalized insights about how your unique DNA combines with your lifestyle factors to influence your disease risks and trait dispositions. Nucleus currently provides reports for the following diseases: ADHD Age-related macular degeneration (AMD) Alcohol dependence Alzheimer's disease Anxiety disorders Asthma Bipolar disorder Celiac disease Colorectal cancer Coronary artery disease Depression Female breast cancer Gastric cancer Hypertension Insomnia Male breast cancer Migraine Multiple sclerosis OCD Parkinson's disease Prostate cancer Rheumatoid arthritis Schizophrenia Type 2 diabetes
What will my results tell me?
add
Your Nucleus results include personalized insights about how your unique DNA combines with your lifestyle factors to influence your disease risks and trait dispositions. Nucleus currently provides reports for the following diseases: ADHD Age-related macular degeneration (AMD) Alcohol dependence Alzheimer's disease Anxiety disorders Asthma Bipolar disorder Celiac disease Colorectal cancer Coronary artery disease Depression Female breast cancer Gastric cancer Hypertension Insomnia Male breast cancer Migraine Multiple sclerosis OCD Parkinson's disease Prostate cancer Rheumatoid arthritis Schizophrenia Type 2 diabetes
What actions can I take based on my results?
add
Nucleus has partnered with SteadyMD to offer board-certified genetic counseling services. While Nucleus is designed to be easy to understand without the help of a doctor, talking with a genetic counselor is the best way to understand your results, especially if you are at high risk for one or more diseases. Genetic counselor appointments via Nucleus cost $99 per one-hour session and are not included with your membership.
What actions can I take based on my results?
add
Nucleus has partnered with SteadyMD to offer board-certified genetic counseling services. While Nucleus is designed to be easy to understand without the help of a doctor, talking with a genetic counselor is the best way to understand your results, especially if you are at high risk for one or more diseases. Genetic counselor appointments via Nucleus cost $99 per one-hour session and are not included with your membership.
What actions can I take based on my results?
add
Nucleus has partnered with SteadyMD to offer board-certified genetic counseling services. While Nucleus is designed to be easy to understand without the help of a doctor, talking with a genetic counselor is the best way to understand your results, especially if you are at high risk for one or more diseases. Genetic counselor appointments via Nucleus cost $99 per one-hour session and are not included with your membership.
Does Nucleus offer a genetic counselor service?
add
Yes. Nucleus has partnered with SteadyMD to offer genetic counseling services. Genetic counselor appointments via Nucleus cost $99 per one-hour session and are not included with your membership.
Does Nucleus offer a genetic counselor service?
add
Yes. Nucleus has partnered with SteadyMD to offer genetic counseling services. Genetic counselor appointments via Nucleus cost $99 per one-hour session and are not included with your membership.
Does Nucleus offer a genetic counselor service?
add
Yes. Nucleus has partnered with SteadyMD to offer genetic counseling services. Genetic counselor appointments via Nucleus cost $99 per one-hour session and are not included with your membership.
Can I download my results?
add
Yes. You can download a physician-ready version of your report from the Nucleus website to share with your doctor. Additionally, you can download your whole-genome DNA files from the Nucleus website at any time.
Can I download my results?
add
Yes. You can download a physician-ready version of your report from the Nucleus website to share with your doctor. Additionally, you can download your whole-genome DNA files from the Nucleus website at any time.
Can I download my results?
add
Yes. You can download a physician-ready version of your report from the Nucleus website to share with your doctor. Additionally, you can download your whole-genome DNA files from the Nucleus website at any time.
Will my results change over time?
add
Yes. While your DNA doesn’t change (it’s yours for life!), your results can. We’re constantly adding new health reports to Nucleus, and we update your existing results as research improves to give you the most accurate read on your health. In addition, as your age and other lifestyle factors change, Nucleus will automatically update to reflect your current health.
Will my results change over time?
add
Yes. While your DNA doesn’t change (it’s yours for life!), your results can. We’re constantly adding new health reports to Nucleus, and we update your existing results as research improves to give you the most accurate read on your health. In addition, as your age and other lifestyle factors change, Nucleus will automatically update to reflect your current health.
Will my results change over time?
add
Yes. While your DNA doesn’t change (it’s yours for life!), your results can. We’re constantly adding new health reports to Nucleus, and we update your existing results as research improves to give you the most accurate read on your health. In addition, as your age and other lifestyle factors change, Nucleus will automatically update to reflect your current health.
Our science
Our science
What is whole-genome sequencing?
add
Most consumer genetic tests use a technology called microarray testing. Microarray tests look at only a tiny fraction of your DNA — less than 0.1%. This means that important health insights can be missed. In comparison, Nucleus looks at closer to 100% of your DNA — 1,000x more DNA than microarray tests — to give you a more complete picture of your health risks. Nucleus performs 30x high-depth whole-genome sequencing coverage.
What is whole-genome sequencing?
add
Most consumer genetic tests use a technology called microarray testing. Microarray tests look at only a tiny fraction of your DNA — less than 0.1%. This means that important health insights can be missed. In comparison, Nucleus looks at closer to 100% of your DNA — 1,000x more DNA than microarray tests — to give you a more complete picture of your health risks. Nucleus performs 30x high-depth whole-genome sequencing coverage.
What is whole-genome sequencing?
add
Most consumer genetic tests use a technology called microarray testing. Microarray tests look at only a tiny fraction of your DNA — less than 0.1%. This means that important health insights can be missed. In comparison, Nucleus looks at closer to 100% of your DNA — 1,000x more DNA than microarray tests — to give you a more complete picture of your health risks. Nucleus performs 30x high-depth whole-genome sequencing coverage.
How does Nucleus analyze my DNA?
add
Nucleus uses whole-genome sequencing to analyze your DNA for millions of variants that can impact your risk for diseases. Nucleus classifies variants into three major categories: Causal, high-effect, and common. Causal variants can single-handedly cause a disease or trait but are extremely rare. High-effect variants have a strong effect on diseases and traits — just one of them can sometimes be enough to substantially increase your chances of developing diseases or having a trait. Common variants are DNA differences more commonly found in people. One common variant alone may not significantly influence your risk of developing a specific disease or your chance of having a certain trait. But, collectively, these variants can shape your traits and influence your disease risks. The combined impact of these variants are measured through our innovative algorithms called common genetic scores (also known as polygenic scores). Through our whole-genome analysis, we are able to identify these variants and provide insights into how they affect your health and well-being.
How does Nucleus analyze my DNA?
add
Nucleus uses whole-genome sequencing to analyze your DNA for millions of variants that can impact your risk for diseases. Nucleus classifies variants into three major categories: Causal, high-effect, and common. Causal variants can single-handedly cause a disease or trait but are extremely rare. High-effect variants have a strong effect on diseases and traits — just one of them can sometimes be enough to substantially increase your chances of developing diseases or having a trait. Common variants are DNA differences more commonly found in people. One common variant alone may not significantly influence your risk of developing a specific disease or your chance of having a certain trait. But, collectively, these variants can shape your traits and influence your disease risks. The combined impact of these variants are measured through our innovative algorithms called common genetic scores (also known as polygenic scores). Through our whole-genome analysis, we are able to identify these variants and provide insights into how they affect your health and well-being.
How does Nucleus analyze my DNA?
add
Nucleus uses whole-genome sequencing to analyze your DNA for millions of variants that can impact your risk for diseases. Nucleus classifies variants into three major categories: Causal, high-effect, and common. Causal variants can single-handedly cause a disease or trait but are extremely rare. High-effect variants have a strong effect on diseases and traits — just one of them can sometimes be enough to substantially increase your chances of developing diseases or having a trait. Common variants are DNA differences more commonly found in people. One common variant alone may not significantly influence your risk of developing a specific disease or your chance of having a certain trait. But, collectively, these variants can shape your traits and influence your disease risks. The combined impact of these variants are measured through our innovative algorithms called common genetic scores (also known as polygenic scores). Through our whole-genome analysis, we are able to identify these variants and provide insights into how they affect your health and well-being.
How accurate is Nucleus?
add
Nucleus’ whole-genome DNA analysis is more than 99.9% accurate. As a clinical-grade 30x test, Nucleus is held to the highest standards to ensure the quality of your DNA analysis.
How accurate is Nucleus?
add
Nucleus’ whole-genome DNA analysis is more than 99.9% accurate. As a clinical-grade 30x test, Nucleus is held to the highest standards to ensure the quality of your DNA analysis.
How accurate is Nucleus?
add
Nucleus’ whole-genome DNA analysis is more than 99.9% accurate. As a clinical-grade 30x test, Nucleus is held to the highest standards to ensure the quality of your DNA analysis.
What genes does Nucleus report on?
add
Nucleus’ Basic and Premium plans currently analyze thousands of genes to provide PRS (polygenic risk scores) for 26 diseases. Additionally, Nucleus Premium analyzes the following genes for pathogenic or likely pathogenic variants: ADHD: AUTS2 CRY1 FGD1 FOXP1 MBD5 MTNR1A NAA15 NF1 NRXN1 SCN1A SETBP1 SLC6A3 SLC9A9 Age-related macular degeneration (AMD): ABCA4 BEST1 C3 C1QTNF5 CDH3 CFH CFI CRB1 CRX CTNNA1 DRAM2 EFEMP1 FBLN5 HMCN1 IMPG1 IMPG2 MFSD8 PRPH2 RAX2 RDH12 RDH5 RLBP1 RP1L1 RPGR RS1 TIMP3 Alzheimer's disease: APP PSEN1 PSEN2 TREM2 Asthma: TNFRSF13B SERPINA1 Bipolar disorder: AKAP11 Celiac disease Chronic pain Colorectal cancer The following colorectal cancer-related genes can be only analyzed in our Premium plan: APC AXIN2 BMPR1A MLH1 MLH3 MSH2 MSH3 MSH6 MUTYH NTHL1 POLD1 POLE PTEN RNF43 SMAD4 STK11 TP53 Coronary artery disease The following coronary artery disease-related genes can be only analyzed in our Premium plan: ABCA1 ABCG5 ABCG8 APOA1 APOA5 APOB APOC2 APOC3 CREB3L3 GPIHBP1 LDLR LDLRAP1 LMF1 LPL PCSK9 Depression Endometriosis Female breast cancer The following female breast cancer-related genes can be only analyzed in our Premium plan: ATM BARD1 BRCA1 BRCA2 BRIP1 CDH1 CHEK2 CTNNA1 NBN NF1 PALB2 PTEN RAD51C RAD51D STK11 TP53 Gastric cancer The following gastric cancer-related genes can be only analyzed in our Premium plan: APC BMPR1A CDH1 CTNNA1 KIT MLH1 MSH2 MSH6 NF1 PDGFRA SDHA SDHAF2 SDHB SDHC SDHD SMAD4 STK11 TP53 Hypertension The following hypertension-related genes can be only analyzed in our Premium plan: ABCC8 ACVRL1 ATP13A3 BMPR2 CACNA1H CAV1 CLCN2 CUL3 CYP11B1 CYP11B2 CYP17A1 EIF2AK4 ENG GDF2 GGCX HSD11B2 KCNJ5 KCNK3 KDR KLHL3 NR3C2 PDE3A SCNN1A SCNN1B SCNN1G SMAD9 TBX4 TET2 WNK1 WNK4 Insomnia We analyze the CRY1 gene for insomnia with our Premium plan Male breast cancer The following male breast cancer-related genes can be only analyzed in our Premium plan: BRCA1 BRCA2 CHEK2 PALB2 Migraine The following migraine-related genes can be only analyzed in our Premium plan: ATP1A2 CACNA1A CACNA1I KCNK18 PRRT2 SCN1A SLC1A3 SLC2A1 Multiple sclerosis OCD Osteoarthritis Ovarian cancer The following ovarian cancer-related genes can be only analyzed in our Premium plan: ATM BARD1 BRCA1 BRCA2 BRIP1 MLH1 MSH2 MSH6 MUTYH PALB2 RAD51C RAD51D SMARCA4 STK11 TP53 Parkinson’s disease The following Parkinson’s disease-related genes can be only analyzed in our Premium plan: ATP13A2 ATP7B CHCHD2 DCTN1 DNAJC6 FBXO7 GCH1 LRRK2 PARK7 PDE8B PINK1 PLA2G6 PRKN PSEN1 PSEN2 RAB39B SLC6A3 SNCA SPR SYNJ1 TH VPS13C VPS35 Polycystic ovarian syndrome (PCOS) Prostate cancer The following prostate cancer-related genes can be only analyzed in our Premium plan: ATM BRCA1 BRCA2 BRIP1 CHEK2 HOXB13 MLH1 MSH2 MSH6 NBN PALB2 RAD51C RAD51D TP53 Restless legs syndrome Rheumatoid arthritis Schizophrenia The following schizophrenia-related genes can be only analyzed in our Premium plan: CACNA1G CUL1 GRIA3 GRIN2A HERC1 RB1CC1 SETD1A SP4 TRIO XPO7 Type 2 diabetes The following type 2 diabetes-related genes can be only analyzed in our Premium plan: ABCC8 CEL DNAJC3 GCK GLUD1 GPD2 HADH HNF1A HNF1B HNF4A INS KCNJ11 NEUROD1 NKX6-1 PDX1 PICK1 RFX6 WFS1
What genes does Nucleus report on?
add
Nucleus’ Basic and Premium plans currently analyze thousands of genes to provide PRS (polygenic risk scores) for 26 diseases. Additionally, Nucleus Premium analyzes the following genes for pathogenic or likely pathogenic variants: ADHD: AUTS2 CRY1 FGD1 FOXP1 MBD5 MTNR1A NAA15 NF1 NRXN1 SCN1A SETBP1 SLC6A3 SLC9A9 Age-related macular degeneration (AMD): ABCA4 BEST1 C3 C1QTNF5 CDH3 CFH CFI CRB1 CRX CTNNA1 DRAM2 EFEMP1 FBLN5 HMCN1 IMPG1 IMPG2 MFSD8 PRPH2 RAX2 RDH12 RDH5 RLBP1 RP1L1 RPGR RS1 TIMP3 Alzheimer's disease: APP PSEN1 PSEN2 TREM2 Asthma: TNFRSF13B SERPINA1 Bipolar disorder: AKAP11 Celiac disease Chronic pain Colorectal cancer The following colorectal cancer-related genes can be only analyzed in our Premium plan: APC AXIN2 BMPR1A MLH1 MLH3 MSH2 MSH3 MSH6 MUTYH NTHL1 POLD1 POLE PTEN RNF43 SMAD4 STK11 TP53 Coronary artery disease The following coronary artery disease-related genes can be only analyzed in our Premium plan: ABCA1 ABCG5 ABCG8 APOA1 APOA5 APOB APOC2 APOC3 CREB3L3 GPIHBP1 LDLR LDLRAP1 LMF1 LPL PCSK9 Depression Endometriosis Female breast cancer The following female breast cancer-related genes can be only analyzed in our Premium plan: ATM BARD1 BRCA1 BRCA2 BRIP1 CDH1 CHEK2 CTNNA1 NBN NF1 PALB2 PTEN RAD51C RAD51D STK11 TP53 Gastric cancer The following gastric cancer-related genes can be only analyzed in our Premium plan: APC BMPR1A CDH1 CTNNA1 KIT MLH1 MSH2 MSH6 NF1 PDGFRA SDHA SDHAF2 SDHB SDHC SDHD SMAD4 STK11 TP53 Hypertension The following hypertension-related genes can be only analyzed in our Premium plan: ABCC8 ACVRL1 ATP13A3 BMPR2 CACNA1H CAV1 CLCN2 CUL3 CYP11B1 CYP11B2 CYP17A1 EIF2AK4 ENG GDF2 GGCX HSD11B2 KCNJ5 KCNK3 KDR KLHL3 NR3C2 PDE3A SCNN1A SCNN1B SCNN1G SMAD9 TBX4 TET2 WNK1 WNK4 Insomnia We analyze the CRY1 gene for insomnia with our Premium plan Male breast cancer The following male breast cancer-related genes can be only analyzed in our Premium plan: BRCA1 BRCA2 CHEK2 PALB2 Migraine The following migraine-related genes can be only analyzed in our Premium plan: ATP1A2 CACNA1A CACNA1I KCNK18 PRRT2 SCN1A SLC1A3 SLC2A1 Multiple sclerosis OCD Osteoarthritis Ovarian cancer The following ovarian cancer-related genes can be only analyzed in our Premium plan: ATM BARD1 BRCA1 BRCA2 BRIP1 MLH1 MSH2 MSH6 MUTYH PALB2 RAD51C RAD51D SMARCA4 STK11 TP53 Parkinson’s disease The following Parkinson’s disease-related genes can be only analyzed in our Premium plan: ATP13A2 ATP7B CHCHD2 DCTN1 DNAJC6 FBXO7 GCH1 LRRK2 PARK7 PDE8B PINK1 PLA2G6 PRKN PSEN1 PSEN2 RAB39B SLC6A3 SNCA SPR SYNJ1 TH VPS13C VPS35 Polycystic ovarian syndrome (PCOS) Prostate cancer The following prostate cancer-related genes can be only analyzed in our Premium plan: ATM BRCA1 BRCA2 BRIP1 CHEK2 HOXB13 MLH1 MSH2 MSH6 NBN PALB2 RAD51C RAD51D TP53 Restless legs syndrome Rheumatoid arthritis Schizophrenia The following schizophrenia-related genes can be only analyzed in our Premium plan: CACNA1G CUL1 GRIA3 GRIN2A HERC1 RB1CC1 SETD1A SP4 TRIO XPO7 Type 2 diabetes The following type 2 diabetes-related genes can be only analyzed in our Premium plan: ABCC8 CEL DNAJC3 GCK GLUD1 GPD2 HADH HNF1A HNF1B HNF4A INS KCNJ11 NEUROD1 NKX6-1 PDX1 PICK1 RFX6 WFS1
What genes does Nucleus report on?
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Nucleus’ Basic and Premium plans currently analyze thousands of genes to provide PRS (polygenic risk scores) for 26 diseases. Additionally, Nucleus Premium analyzes the following genes for pathogenic or likely pathogenic variants: ADHD: AUTS2 CRY1 FGD1 FOXP1 MBD5 MTNR1A NAA15 NF1 NRXN1 SCN1A SETBP1 SLC6A3 SLC9A9 Age-related macular degeneration (AMD): ABCA4 BEST1 C3 C1QTNF5 CDH3 CFH CFI CRB1 CRX CTNNA1 DRAM2 EFEMP1 FBLN5 HMCN1 IMPG1 IMPG2 MFSD8 PRPH2 RAX2 RDH12 RDH5 RLBP1 RP1L1 RPGR RS1 TIMP3 Alzheimer's disease: APP PSEN1 PSEN2 TREM2 Asthma: TNFRSF13B SERPINA1 Bipolar disorder: AKAP11 Celiac disease Chronic pain Colorectal cancer The following colorectal cancer-related genes can be only analyzed in our Premium plan: APC AXIN2 BMPR1A MLH1 MLH3 MSH2 MSH3 MSH6 MUTYH NTHL1 POLD1 POLE PTEN RNF43 SMAD4 STK11 TP53 Coronary artery disease The following coronary artery disease-related genes can be only analyzed in our Premium plan: ABCA1 ABCG5 ABCG8 APOA1 APOA5 APOB APOC2 APOC3 CREB3L3 GPIHBP1 LDLR LDLRAP1 LMF1 LPL PCSK9 Depression Endometriosis Female breast cancer The following female breast cancer-related genes can be only analyzed in our Premium plan: ATM BARD1 BRCA1 BRCA2 BRIP1 CDH1 CHEK2 CTNNA1 NBN NF1 PALB2 PTEN RAD51C RAD51D STK11 TP53 Gastric cancer The following gastric cancer-related genes can be only analyzed in our Premium plan: APC BMPR1A CDH1 CTNNA1 KIT MLH1 MSH2 MSH6 NF1 PDGFRA SDHA SDHAF2 SDHB SDHC SDHD SMAD4 STK11 TP53 Hypertension The following hypertension-related genes can be only analyzed in our Premium plan: ABCC8 ACVRL1 ATP13A3 BMPR2 CACNA1H CAV1 CLCN2 CUL3 CYP11B1 CYP11B2 CYP17A1 EIF2AK4 ENG GDF2 GGCX HSD11B2 KCNJ5 KCNK3 KDR KLHL3 NR3C2 PDE3A SCNN1A SCNN1B SCNN1G SMAD9 TBX4 TET2 WNK1 WNK4 Insomnia We analyze the CRY1 gene for insomnia with our Premium plan Male breast cancer The following male breast cancer-related genes can be only analyzed in our Premium plan: BRCA1 BRCA2 CHEK2 PALB2 Migraine The following migraine-related genes can be only analyzed in our Premium plan: ATP1A2 CACNA1A CACNA1I KCNK18 PRRT2 SCN1A SLC1A3 SLC2A1 Multiple sclerosis OCD Osteoarthritis Ovarian cancer The following ovarian cancer-related genes can be only analyzed in our Premium plan: ATM BARD1 BRCA1 BRCA2 BRIP1 MLH1 MSH2 MSH6 MUTYH PALB2 RAD51C RAD51D SMARCA4 STK11 TP53 Parkinson’s disease The following Parkinson’s disease-related genes can be only analyzed in our Premium plan: ATP13A2 ATP7B CHCHD2 DCTN1 DNAJC6 FBXO7 GCH1 LRRK2 PARK7 PDE8B PINK1 PLA2G6 PRKN PSEN1 PSEN2 RAB39B SLC6A3 SNCA SPR SYNJ1 TH VPS13C VPS35 Polycystic ovarian syndrome (PCOS) Prostate cancer The following prostate cancer-related genes can be only analyzed in our Premium plan: ATM BRCA1 BRCA2 BRIP1 CHEK2 HOXB13 MLH1 MSH2 MSH6 NBN PALB2 RAD51C RAD51D TP53 Restless legs syndrome Rheumatoid arthritis Schizophrenia The following schizophrenia-related genes can be only analyzed in our Premium plan: CACNA1G CUL1 GRIA3 GRIN2A HERC1 RB1CC1 SETD1A SP4 TRIO XPO7 Type 2 diabetes The following type 2 diabetes-related genes can be only analyzed in our Premium plan: ABCC8 CEL DNAJC3 GCK GLUD1 GPD2 HADH HNF1A HNF1B HNF4A INS KCNJ11 NEUROD1 NKX6-1 PDX1 PICK1 RFX6 WFS1
Data and privacy
Data and privacy
How secure and private is Nucleus?
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Your privacy is our highest priority. In addition to being HIPAA-compliant, CLIA-certified, and CAP-accredited, we require all of our users to sign in with 2-factor authentication to ensure the security of your DNA sample, your DNA test results, and other personal data you provide to us. Your cheek DNA sample will be safely destroyed within 60 days of being received by the lab. You own your DNA data. You can download your DNA file(s) at any time. We do not share your DNA or health data with third parties, except as legally required or with your explicit consent.
How secure and private is Nucleus?
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Your privacy is our highest priority. In addition to being HIPAA-compliant, CLIA-certified, and CAP-accredited, we require all of our users to sign in with 2-factor authentication to ensure the security of your DNA sample, your DNA test results, and other personal data you provide to us. Your cheek DNA sample will be safely destroyed within 60 days of being received by the lab. You own your DNA data. You can download your DNA file(s) at any time. We do not share your DNA or health data with third parties, except as legally required or with your explicit consent.
How secure and private is Nucleus?
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Your privacy is our highest priority. In addition to being HIPAA-compliant, CLIA-certified, and CAP-accredited, we require all of our users to sign in with 2-factor authentication to ensure the security of your DNA sample, your DNA test results, and other personal data you provide to us. Your cheek DNA sample will be safely destroyed within 60 days of being received by the lab. You own your DNA data. You can download your DNA file(s) at any time. We do not share your DNA or health data with third parties, except as legally required or with your explicit consent.
Where is my DNA sample sequenced?
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Nucleus is proud to sequence your DNA 100% in the United States. Your DNA is never sent or stored overseas.
Where is my DNA sample sequenced?
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Nucleus is proud to sequence your DNA 100% in the United States. Your DNA is never sent or stored overseas.
Where is my DNA sample sequenced?
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Nucleus is proud to sequence your DNA 100% in the United States. Your DNA is never sent or stored overseas.
What happens to my sample after it’s sequenced?
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Your DNA sample sent to the laboratory will be safely destroyed within 60 days of being received by the lab, guaranteed. As an additional measure of privacy and security, we remove your identity from your DNA sample throughout the testing process.
What happens to my sample after it’s sequenced?
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Your DNA sample sent to the laboratory will be safely destroyed within 60 days of being received by the lab, guaranteed. As an additional measure of privacy and security, we remove your identity from your DNA sample throughout the testing process.
What happens to my sample after it’s sequenced?
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Your DNA sample sent to the laboratory will be safely destroyed within 60 days of being received by the lab, guaranteed. As an additional measure of privacy and security, we remove your identity from your DNA sample throughout the testing process.
Can I download my whole-genome file?
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Yes. You can download your raw whole-genome DNA files (FASTQ or VCF) from the Nucleus website at any time. Upon request, you’ll receive an email with your DNA file(s).
Can I download my whole-genome file?
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Yes. You can download your raw whole-genome DNA files (FASTQ or VCF) from the Nucleus website at any time. Upon request, you’ll receive an email with your DNA file(s).
Can I download my whole-genome file?
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Yes. You can download your raw whole-genome DNA files (FASTQ or VCF) from the Nucleus website at any time. Upon request, you’ll receive an email with your DNA file(s).
Is Nucleus regulated?
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Yes. Nucleus is HIPAA-compliant, CLIA-certified, and CAP-accredited. This means that we follow strict scientific guidelines and are legally required to protect your protected health information (PHI).
Is Nucleus regulated?
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Yes. Nucleus is HIPAA-compliant, CLIA-certified, and CAP-accredited. This means that we follow strict scientific guidelines and are legally required to protect your protected health information (PHI).
Is Nucleus regulated?
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Yes. Nucleus is HIPAA-compliant, CLIA-certified, and CAP-accredited. This means that we follow strict scientific guidelines and are legally required to protect your protected health information (PHI).
Membership info
Membership info
Why is there a membership fee?
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Genetic research is always improving, and we’re committed to keeping you in the know. Your membership gives you updated reports and insights that are at the cutting-edge of genetic research.
Why is there a membership fee?
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Genetic research is always improving, and we’re committed to keeping you in the know. Your membership gives you updated reports and insights that are at the cutting-edge of genetic research.
Why is there a membership fee?
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Genetic research is always improving, and we’re committed to keeping you in the know. Your membership gives you updated reports and insights that are at the cutting-edge of genetic research.
What’s included with my membership?
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Your membership includes all of Nucleus’ health reports — now and in the future. Your reports will update automatically to reflect your current health with new research, analyses, and changes to your lifestyle factors.
What’s included with my membership?
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Your membership includes all of Nucleus’ health reports — now and in the future. Your reports will update automatically to reflect your current health with new research, analyses, and changes to your lifestyle factors.
What’s included with my membership?
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Your membership includes all of Nucleus’ health reports — now and in the future. Your reports will update automatically to reflect your current health with new research, analyses, and changes to your lifestyle factors.
Are genetic counselor appointments included?
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No. Genetic counselor appointments on Nucleus cost $99 per one-hour session and are not included with your membership.
Are genetic counselor appointments included?
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No. Genetic counselor appointments on Nucleus cost $99 per one-hour session and are not included with your membership.
Are genetic counselor appointments included?
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No. Genetic counselor appointments on Nucleus cost $99 per one-hour session and are not included with your membership.
One test. All your DNA. For $399.
One test. All your DNA. For $399.
One test. All your DNA. For $399.
Have a question?
Join the movement
HIPAA COMPLIANT
CLIA CERTIFIED
CAP accredited
sequenced in the u.s.
Made in the U.S.A.
@ 2024 Nucleus Genomics, Inc.
HIPAA COMPLIANT
CLIA CERTIFIED
CAP accredited
sequenced in the u.s.
Made in the U.S.A.
@ 2024 Nucleus Genomics, Inc.
Join the movement
HIPAA
CLIA
CAP
sequenced in the u.s.
Made in the U.S.A.
@ 2024 Nucleus Genomics, Inc.