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How it works

With just one cheek swab, Nucleus uncovers your genetic risk for 2000+ conditions — for you and your future kids.

Nucleus comes in two parts:

Part 1

Test kit

Our clinical-grade, at-home genetic test gives you a deep look at your entire genome—all your DNA.

Our clinical-grade, at-home genetic test gives you a deep look at your entire genome—all your DNA.

Swab your cheek

Testing at home is easy—a simple cheek swab is all it takes to collect your whole-genome DNA sample.

Send your sample

Mail your sample to the lab using the pre-paid envelope included with your kit.

Get your results

Once your sample arrives at the lab, you'll receive your results in about 4-6 weeks.

Part 2

Membership

Access your test results on the Nucleus platform and start taking action to protect your health and future family.

Access your test results on the Nucleus platform and start taking action to protect your health and future family.

Nucleus Preview

Find out which diseases you’re a carrier for and how to prevent passing them on.

Nucleus Health

Uncover your genetic risk for 2000+ conditions, including cancers, heart conditions, mental health, and more.

Nucleus AI

Get personalized health tips to reduce your risk for disease in the future.

Testing is easy.

1

Swab your cheek

Testing at home is easy — simply swab your cheek to collect your genetic sample.

2

Send your sample

"I like being a freelancer because you get to work on diverse projects. It’s learning about different subjects that I really enjoy."

3

Get your results

"I like being a freelancer because you get to work on diverse projects. It’s learning about different subjects that I really enjoy."

1

Swab your cheek

Testing at home is easy — simply swab your cheek to collect your genetic sample.

2

Send your sample

"I like being a freelancer because you get to work on diverse projects. It’s learning about different subjects that I really enjoy."

3

Get your results

"I like being a freelancer because you get to work on diverse projects. It’s learning about different subjects that I really enjoy."

1

Swab your cheek

Testing at home is easy — simply swab your cheek to collect your genetic sample.

2

Send your sample

"I like being a freelancer because you get to work on diverse projects. It’s learning about different subjects that I really enjoy."

3

Get your results

"I like being a freelancer because you get to work on diverse projects. It’s learning about different subjects that I really enjoy."

More DNA means better insights.

1,000x

more DNA sequenced with Nucleus*

*compared to 23andMe, Ancestry, and similar tests

Other tests*

100% of your DNA

Less than 0.1% of your DNA

More DNA means better insights.

1,000x

more DNA sequenced with Nucleus*

*compared to 23andMe, Ancestry, and similar tests

Other tests*

100% of your DNA

0.1% of your DNA

More DNA means better insights.

1,000x

more DNA sequenced with Nucleus*

*compared to 23andMe, Ancestry, and similar tests

Other tests*

100%

0.1%

One swab.

2,000+ screenings.

Included with Nucleus:

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Cancers

Nucleus provides genetic screening for hundreds of cancers and cancer-related diseases, including:


  • Breast cancer (female)

  • Colorectal cancer

  • Male breast cancer (male)

  • Ovarian cancer (female)

  • Prostate cancer (male)

  • See full list

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Heart health

Nucleus provides genetic screening for hundreds of heart-related diseases, including:


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Mental health

Nucleus provides genetic screening for hundreds of mental health conditions, including:


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Brain health

Nucleus provides genetic screening for hundreds of neurological diseases, including:


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Metabolic health

Nucleus provides genetic screening for hundreds of diseases impacting food and diet, including:


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Skin health

Nucleus provides genetic screening for hundreds of conditions that impact your hair and skin, including:


One swab.

2,000+ screenings.

Included with Nucleus:

check

Cancers

Nucleus provides genetic screening for hundreds of cancers and cancer-related diseases, including:


  • Breast cancer (female)

  • Colorectal cancer

  • Male breast cancer (male)

  • Ovarian cancer (female)

  • Prostate cancer (male)

  • See full list

check

Heart health

Nucleus provides genetic screening for hundreds of heart-related diseases, including:


check

Mental health

Nucleus provides genetic screening for hundreds of mental health conditions, including:


check

Brain health

Nucleus provides genetic screening for hundreds of neurological diseases, including:


check

Metabolic health

Nucleus provides genetic screening for hundreds of diseases impacting food and diet, including:


check

Skin health

Nucleus provides genetic screening for hundreds of conditions that impact your hair and skin, including:


Invest in your future.

What could cost you thousands is $499.

What could cost you thousands is $499.

Nucleus covers

Nucleus covers

Nucleus covers

Cost on your own*

Cancer screening

Cancer screening

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$300

$300

Carrier screening

Carrier screening

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$449

$449

Heart screening

Heart screening

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$300

$300

Neurology screening

Neurology screening

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$250

$250

Total cost

Total cost

Total cost

$499

$499

$499

$1,299

$1,299

$1,299

*Based on Blueprint Genomics and Natera prices as of June 2024.

Questions? Answers.

FAQs

What is Nucleus?

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Nucleus offers a complete family planning experience, from preconception genetic testing to advanced embryo analysis and IVF care. We help you understand your own genetics and your future child’s, so you can plan with more clarity and confidence.

Where should I start?

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It depends where you are in your journey.

If you’re interested in understanding your own health, Nucleus Health is a comprehensive genetic test that screens for over 2000 conditions you may be at risk for. These insights give you a clearer picture of your health today, and help you start more informed conversations with your doctor and other medical experts about any next steps. 

If you’re just starting to think about having a child, Nucleus Preview is a simple first step and where Nucleus’ family planning services begin. It helps you and your partner understand what you might pass on, before conception. 

If you’re already going through IVF, Nucleus Embryo gives you a clearer picture of your embryos so you can choose with more confidence. It’s easily integrated into any existing IVF care. 

If you’re planning to do IVF and want a more supported experience, Nucleus IVF+ brings everything together in one seamless path, from clinic matching through to advanced genetic analysis and pregnancy.

Not sure where to begin? We’re always here to help you figure it out. Reach out to our concierge team anytime - concierge@mynucleus.com.

How should I use this information?

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Our genetic insights are here to give you more information, not to tell you what to do.

With Health, results typically help people make more informed lifestyle decisions, understand what to watch out for over time, and serve as a starting point for conversations with their doctor about any appropriate next steps.

With Preview, many people use their results to plan ahead for children, understand their own potential health risks, and have more informed conversations with their doctor. Some go on to conceive naturally, just with more clarity, while others explore IVF if it feels right for them.

For Embryo, the insights are used by the parents to compare embryos and make their own decisions during IVF.

How do I get my results?

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Your results are delivered in your Nucleus account through clear, easy-to-understand reports.

You can access them anytime, and if you have questions, a genetic counselor is available to talk everything through with you.

How accurate are Nucleus’ results?

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Nucleus’ whole-genome DNA analysis is more than 99.9% accurate. As a clinical-grade test, we’re held to the highest standards to ensure the quality of your DNA analysis. 

That said, it’s important to understand how different types of genetic results work.

Some conditions are caused by a single gene. In those cases, results can be highly definitive, showing whether a specific variant is present or not.

But most health conditions and traits, like cancer risk, heart disease, or height, are influenced by many genes working together. These results are probabilistic, not certain. They reflect likelihood, not guarantees.

That’s not a limitation of Nucleus — it’s how genetics works. Environment, lifestyle, and chance also play a role. Nucleus helps you understand risk and possibilities, so you can make more informed decisions.

Why did my Nucleus results change?

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While your DNA doesn’t change, how we analyze it can and does change your results. With more data and improved methods, your genetic insights will update over time to reflect the latest science. Our goal is to ensure your results always represent the most accurate picture of what’s known today.

Some conditions are driven by a single gene, where results are clear and unchanging. Others, like most common diseases and traits, are shaped by many genes working together. These insights are estimates of likelihood, not definitive predictions—and may evolve as the science improves.

Like a weather forecast, your results become more precise as more information and better models become available. Earlier results weren’t wrong, just less refined.

Do I need to be doing IVF to do Nucleus?

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Not at all. Nucleus is designed for many different paths to parenthood, as well as individual health insights.

If you’re still early in your journey, we recommend starting with Nucleus Preview. It gives couples (and individuals) insight into what could be passed on to your future child, so you have more information, whatever path you take. 

And if you simply want to learn more about your own health, Nucleus Health uncovers your risk for 2000+ conditions, so you can prevent future disease and live healthier, longer.

How much does Nucleus cost?

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In the U.S., Nucleus’ offerings are priced as follows:

  • Nucleus Health is $499, including one DNA kit + $39/year/person membership

  • Nucleus Preview is $949, including two DNA kits + $39/year/person membership

  • Nucleus Embryo is $9,999

  • Nucleus IVF+ is as little as $9,999/month for four months, depending on clinic location.

How long does Nucleus take?

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Timings vary depending on where you are in your journey and which Nucleus offering you choose.

  • Preview and Health
    Once you place your order, we’ll send everything you need, including your test kits. Collecting your sample is simple with a quick cheek swab. After you send it back using the prepaid label, your results are typically ready within 4-6 weeks.

  • Embryo
    Timelines depend on your clinic and lab. Once we receive your embryo data, your analysis is usually ready within 1–2 weeks.

  • IVF+
    IVF+ follows the natural timeline of IVF. Because it’s built around your care, timing will depend on your individual treatment plan but we’ll guide you every step of the way.

Will someone help me understand my results?

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Yes. You’ll have access to genetic counselors who can walk you through your results and help you understand what they mean for you. 

If you’re doing Nucleus Embryo or IVF+, your Nucleus results will also be shared with your existing IVF care team, including your physician, so you feel supported from every angle.

Uncover your health insights

Uncover your health insights