March 31, 2025

March 31, 2025

Bryan Johnson’s Don’t Die Summit: An in-depth overview

Bryan Johnson’s Don’t Die Summit: An in-depth overview

Learn what to expect from the Don’t Die Summit and whether it’s worth attending. Discover the schedule, locations, and central themes covered in the event.

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Bryan Johnson quickly became one of the most prominent figures in the longevity space and for a good reason. After launching the Blueprint Protocol based on cutting-edge science, the multi-millionaire techpreneur decided to share his unconventional but undoubtedly effective methods through the Don’t Die Summit.

The one-of-a-kind global event explores the latest health optimization trends and techniques, and is backed by industry leaders in the biohacking space. In this guide, you’ll learn if it lives up to the outstanding traction it’s gained.

Specifically, we’ll cover:

  • The event’s purpose and target audience

  • The main themes and activities covered by the event

  • Don’t Die Summit schedule and locations

  • The event’s main backers and sponsors


What is Bryan Johnson’s Don’t Die Summit?


The Don’t Die Summit is a tech-forward event focused on emerging technologies and innovative techniques related to health optimization, longevity, and age reversal. Here are some quick facts you should know:

|              |                                             |
| ------------ | ------------------------------------------- |
| Event format | Live (no streaming or on-demand viewing)    |
| Duration     | One day                                     |
| Focus areas  | Biohacking, anti-aging, wellness innovation |
| Location     | Worldwide

The summit attracts individuals from all walks of life who are interested in increasing their lifespans and living healthier lives, though it’s most commonly attended by:

  • Biohacking experts

  • Fitness enthusiasts

  • Wellness professionals

  • Health optimization companies

The event was named after Johnson’s “Don’t Die” movement, which aims to introduce a new era of health and wellness. The movement’s ambitious mission is to promote the idea that death is no longer inescapable, so the Don’t Die Summit brings together individuals and companies who wish to contribute to this goal through their expertise and solutions.


What to expect at the Don’t Die Summit

While the specifics of the Don’t Die Summit vary between individual events, the focus is always on the latest and greatest in the biohacking and longevity areas. Some of the summit’s highlights include:

  • Expert-led discussions on topics like bioengineering, medical research, artificial intelligence, and more

  • Interactive booths showcasing cutting-edge longevity products and therapies (e.g., attendants get to discover their biological age and other aspects of their well-being)

  • Practical demonstrations of different biohacking solutions

  • Networking opportunities for researchers, tech entrepreneurs, investors, and other individuals interested in health and wellness

As for the specific themes covered during the summit, the most notable ones include:

  1. Stem cell therapies

  2. Preventive medicine and longevity therapies

  3. Hair and skin care

  4. Personalized nutrition

  5. Whole-genome DNA testing

Below we’ll cover each of these topics in more detail.


Stem cell therapies

Stem cell therapy isn’t a new concept, but biohacking pioneers like Johnson are exploring new ways to use it for age reversal and longevity. In 2024, Johnson famously injected his joints with 300 million bone marrow mesenchymal stem cells to achieve age 18 joints, with results yet to be seen as of this writing.


Full post: Instagram

Considering the potential of stem cell therapy across longevity-related procedures, it doesn’t come as a surprise that the Don’t Die Summit places a particular focus on it.


Preventive medicine and longevity therapies

Popularized by the likes of Andrew Huberman, Peter Attia, and other big names in scientific circles, preventive medicine is a new approach to health that emphasizes the value of being proactive. It’s an unavoidable part of Johnson’s quest toward eternal life, so you can expect to hear a lot about it at the summit.

From his 14-step anti-aging morning routine to vigorous workouts and procedures aimed at keeping disease at bay, Johnson has explored numerous effective longevity therapies. If you’re interested in the steps you can take to avoid preventable conditions, the summit might be a place for you.


Hair and skin care

After successfully reversing hair loss and graying, Johnson became one of the go-to sources of hair and skin care advice in biohacking circles. His extensive skincare regimen goes far beyond the basics and includes advanced methods like microneedling and ultrasounds, so you can expect to hear more about these cutting-edge approaches.


Full post: Instagram

Depending on when you visit the event, you might also get a chance to explore innovative products from companies like Roots by Genetic Arts, which offers prescription hair loss solutions based on a person’s genetic makeup.


Personalized nutrition


Bryan Johnson’s diet is packed with superfoods and supplements, all tailored to his unique biochemistry and age-reversal goals. He’s a major proponent of a personalized approach to nutrition, which you can explore in greater detail at the Don’t Die Summit.

You’ll also get a chance to witness innovation in the food and supplement spaces, from macadamia-based longevity solutions to coffee with functional mushrooms and collagen protein.


Genetic procedures and DNA testing

Gene therapy is an essential component of Bryan Johnson’s anti-aging efforts. In 2023, he traveled to Honduras to undergo an experimental gene-editing procedure intended to enhance muscle growth and repair. The therapy currently costs $25,000, making it unviable for public application. 

However, Johnson is also a big proponent of DNA testing, which is much more accessible to the average person. Understanding your genome and its many variations through whole-genome DNA sequencing would be a more logical and less invasive approach before considering advanced gene-editing interventions.


Full post: Instagram

Unlike genotyping, which only captures a small fragment of your genome, whole-genome DNA sequencing analyses almost 100% of your DNA to uncover hundreds of genetic predispositions and disease risk factors.

This way, you can make informed decisions about nutrition, exercise, and various other aspects of a healthy lifestyle to maximize the results of your longevity endeavors.

Due to the value of whole-genome sequencing, it’s not surprising that the Don’t Die Summit includes it as one of the key themes. By attending the summit, you can learn more about the sequencing process firsthand and learn how cutting-edge DNA analysis provides insights into disease risk, metabolism, and longevity optimization.


Don’t Die Summit schedule and locations


While the specific activities can vary between events, the typical schedule of the Don’t Die Summit looks like this:

| Activity                                                 | Time                         |
| -------------------------------------------------------- | ---------------------------- |
| Morning rave                                             | 9 am–10 am                   |
| Blueprint and longevity talks                            | Varying time slots           |
| The World’s Healthiest Lunch                             | 12 pm–2 pm                   |
| Bio-age testing                                          | All day (9 am–5 pm)          |
| Longevity therapy, testing, and technology presentations | All day (9 am–5 pm)          |
| After party                                              | Late afternoon/evening hours

Johnson held the first Don’t Die Summit in 2024 in San Francisco, followed by Singapore and Los Angeles. Other locations where the event is expected to take place include:

  • New York

  • Miami

  • Austin

  • Chicago

  • Seattle

  • Phoenix

  • Atlanta

You can register for the Don’t Die Summit on the official website. Dates and ticket prices will become available as the specific event approaches. If you want to secure the tickets for your chosen event, you can choose to be notified about its dates in each city.

Depending on the venue, the event’s capacity is 1,000–1,500 attendees. Tickets tend to sell out quickly, so you may need to act fast to reserve your spot.


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Don’t Die Summit partners and sponsors

The Don’t Die Summit partners with innovative health optimization companies aligned with Bryan Johnson’s longevity philosophy. Some of the most notable partners and sponsors include: 

  1. Nucleus

  2. Eight Sleep

  3. Acorn

  4. iRestore

  5. Filter Optix


Nucleus

Nucleus is a comprehensive DNA platform that uses whole-genome sequencing to analyze almost 100% of your genome with 99% accuracy. All you need to do is provide a DNA sample through a cheek swab, and Nucleus will conduct over 900 screenings to uncover:

  • Risks of numerous diseases and conditions (cardiovascular diseases, cancers, depression and anxiety, etc.)

  • Health predispositions related to various organs and systems (respiratory, digestive, hormonal, etc.)

  • Predispositions for common neurological diseases (Parkinson's, Alzheimer's, etc.)


The cutting-edge technology powering Nucleus encompasses several factors besides your genetic makeup, such as:

  • Age

  • Sex

  • BMI

  • Blood pressure

  • Smoking status

By integrating this data, Nucleus provides highly personalized reports with actionable guidance on nutrition, supplementation, and other lifestyle factors impacting your overall well-being.

If you want to explore these and many other features of the platform, sign up for Nucleus Premium to get started.


Eight Sleep

Eight Sleep advertises itself as a sleep fitness company, helping you maximize sleep quality through its tech-forward solutions. The company’s flagship product is the Pod 4 Ultra, a mattress packed with innovative technologies and features, such as:

  • Automated temperature regulation for each side of the mattress (55–110° F)

  • Snoring detection and mitigation through automatic posture adjustment

  • Clinical-grade sensors for tracking sleep metrics with 99% accuracy

If you don’t need as many features in your mattress, you can also choose Pod 4 and Pod 3 as simpler and more affordable solutions.


Acorn

Acorn offers personalized regenerative medicine based on stem cells. Through its service, you can extract and preserve your younger cells through cryogenic freezing for personalized topical treatments, such as:

  • Skin rejuvenation

  • Hair regrowth

  • Injury recovery

  • Disease treatment

Acorn launched an exclusive offer for Don’t Die Summit attendees, so you can get 20% off by pre-registering.


iRestore

iRestore is one of the most prominent providers of the increasingly popular red light therapy solutions. Its products are designed to promote hair regrowth and skin rejuvenation in a simple and non-invasive way.

The product leverages low-level laser therapy (LLLT), which has various benefits, including:

  • Increased cell metabolism

  • Improved circulation

  • Cell stimulation

iRestore is one of the key Don’t Die Summit partners, so you can explore the company’s solutions by attending it.


Full post: Instagram


Filter Optix

Filtex Optix specializes in high-quality blue light glasses, which can be a useful addition to your preventive medicine efforts. The glasses use advanced blue light-blocking technology to help prevent eye strain and balance the circadian rhythm, providing higher-quality sleep.

The lenses are FDA-approved and come in four different colors and three variants:

  • Non-prescription

  • Prescription

  • Reading


Should you attend the Don’t Die Summit?

You should attend the Don’t Die Summit if you’re interested in the latest trends and technologies in preventive medicine, longevity, and anti-age solutions. The summit is also a place where you can meet like-minded individuals and network with industry leaders.

If you’ve missed some of the past events, you can explore previous attendees’ experiences to learn more about what you can expect. As it’s a recurring event taking place in various locations, you shouldn’t have trouble securing your spot at one of the future summits.


Beyond the summit: Netflix's Don't Die documentary


Source: Netflix screenshot

If you want to learn more about Bryan Johnson before visiting the Don’t Die Summit or gain a more personal perspective on his longevity journey, you should check out Netflix’s Don’t Die documentary.

Unlike the Don’t Die Summit, which provides a public, interactive experience, the documentary takes an introspective approach to Johnson’s pursuit of a long (or even eternal) life. You’ll get a thorough insight into his self-experimentation initiatives, uncovering both the science behind his longevity protocols and the personal challenges he faces in his pursuit of a longer life.

The documentary is engaging and informative even if you haven’t followed Johnson’s endeavors but are interested in the concept of longevity and health-related topics. Some of the key insights you’ll get include:

  • A detailed overview of the Blueprint Protocol

  • Key motivations behind Johnson’s journey

  • A summary of Johnson’s data-driven longevity tactics

On the more personal end, the documentary explores essential questions like what makes a long life fulfilling, touching on topics like relationships and human connection. It also covers broader dilemmas surrounding biohacking, discussing its ethical implications.


[Reddit](https://www.reddit.com/r/blueprint_/comments/1hreclr/comment/m55f1ks)


Whether you only watch the documentary or also visit the Don’t Die Summit, you’ll most likely be inspired to explore health and longevity more deeply. While doing so, remember that many of Johnson’s favorite methods are neither accessible to everyone nor universally applicable, so you should find a way to adapt them to your unique anatomy, physiology, and biochemistry.

Since genetics play a vital role in these factors and the underlying mechanisms guiding your well-being, understanding your genome should be a starting point on your longevity journey. To do so, follow these steps to get started with Nucleus Premium:

  1. Sign up for Nucleus Premium

  2. Provide your personal information

  3. Place the order

Any questions or still unsure?

Ask our team

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Made in the U.S.A.

© 2025 Nucleus Genomics, Inc.

Any questions or still unsure?

Ask our team

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Join the movement

© 2025 Nucleus Genomics, Inc.

HIPAA-COMPLIANT

CLIA-CERTIFIED

CAP-accredited

Made in the U.S.A.

Any questions or still unsure?

Ask our team

arrow_outward

Join the movement

HIPAA-COMPLIANT

CLIA-CERTIFIED

CAP-accredited

Made in the U.S.A.

© 2025 Nucleus Genomics, Inc.

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