task_alt
FSA/HSA eligible
All-in-one
The DNA
DNA health test
health test
Nucleus gives you dramatically better health insights by sequencing 1,000x more DNA than 23andMe.
Nucleus gives you dramatically better health insights by sequencing 1,000x more DNA than 23andMe.
Introducing
Uncover the diseases you and your partner could pass on to your children — before you have kids.
task_alt
FSA/HSA
eligible
Introducing
Uncover the diseases you and your partner could pass on to your children — before you have kids.
task_alt
FSA/HSA
eligible
Introducing
Uncover the diseases you and your partner could pass on to your children — before you have kids.
task_alt
FSA/HSA
eligible
One test.
900+ screenings.
Nucleus uncovers your genetic risk for 900+ conditions — cancers, heart disease, mental health, and more.
Heart disease
Migraine
Insomnia
ADHD
Longevity
Type 2 diabetes
Gastric cancer
Intelligence (IQ)
Hypertension
Alcoholism
Alzheimer's
Breast cancer
Heart disease
Migraine
Insomnia
ADHD
Hypertension
Alcoholism
Type 2 diabetes
Gastric cancer
Breast cancer
Alzheimer's
Intelligence (IQ)
Longevity
Coronary artery disease
Anxiety disorders
Arthritis
Celiac disease
Prostate cancer
Restless legs syndrome
More DNA means better insights.
1,000x
more DNA sequenced with Nucleus*
*compared to 23andMe, Ancestry, and similar tests
100% of your DNA
Less than 0.1% of your DNA
Less than 0.1% of your DNA
More DNA means better insights.
1,000x
more DNA sequenced with Nucleus*
*compared to 23andMe, Ancestry, and similar tests
100% of your DNA
0.1% of your DNA
0.1% of your DNA
More DNA means better insights.
1,000x
more DNA sequenced with Nucleus*
*compared to 23andMe, Ancestry, and similar tests
100%
0.1%
See why we’re the
#1 DNA test.
Just found that my genetic risk of diabetes is higher than 99.9% who share the same ancestry as me. This stuff is priceless.
Yasir A
Reassuring to see i have normal or below average risks for stuff like heart disease, high blood pressure, type 2 diabetes, several types of cancer, arthritis.
Erica W
Nucleus confirmed the knowledge I already have about my family history, but I also found out that I'm at elevated risk for coronary artery disease, insomnia, and multiple sclerosis.
Maxx Y
I discovered I was at a very high risk for a condition I’d never even heard of—Hereditary Hemochromatosis—which would ultimately change my life.
Ethan C
As the father of two girls (and son of a mom who had breast cancer), I'm grateful to know about my disease risks so we can plan better as a family.
Alexis O
The process couldn’t have been more straightforward. No blood draws…no Dr. visits…just a quick swab of my cheeks.
Jeffrey B
I got the results! I am actually quite impressed. . . the most accurate test I've taken.
Johnny S
Got my results yesterday. Pretty amazing insights, especially one in particular that I wasn’t even aware could be related to genomics and had a deep impact on my life: alcohol.
Gabriel V
Nucleus highlights factors like age, BMI, or cholesterol that are likely to tilt the scales in certain cases. I now plan to have more regular eye exams because my risk for macular degeneration is more strongly correlated with age than I knew.
Michael Hendricks
See why we’re the
#1 DNA test.
Just found that my genetic risk of diabetes is higher than 99.9% who share the same ancestry as me. This stuff is priceless.
Yasir A
Reassuring to see i have normal or below average risks for stuff like heart disease, high blood pressure, type 2 diabetes, several types of cancer, arthritis.
Erica W
Nucleus confirmed the knowledge I already have about my family history, but I also found out that I'm at elevated risk for coronary artery disease, insomnia, and multiple sclerosis.
Maxx Y
I discovered I was at a very high risk for a condition I’d never even heard of—Hereditary Hemochromatosis—which would ultimately change my life.
Ethan C
As the father of two girls (and son of a mom who had breast cancer), I'm grateful to know about my disease risks so we can plan better as a family.
Alexis O
The process couldn’t have been more straightforward. No blood draws…no Dr. visits…just a quick swab of my cheeks.
Jeffrey B
I got the results! I am actually quite impressed. . . the most accurate test I've taken.
Johnny S
Got my results yesterday. Pretty amazing insights, especially one in particular that I wasn’t even aware could be related to genomics and had a deep impact on my life: alcohol.
Gabriel V
Nucleus highlights factors like age, BMI, or cholesterol that are likely to tilt the scales in certain cases. I now plan to have more regular eye exams because my risk for macular degeneration is more strongly correlated with age than I knew.
Michael Hendricks
See why we’re the
#1 DNA test.
Just found that my genetic risk of diabetes is higher than 99.9% who share the same ancestry as me. This stuff is priceless.
Yasir A
Reassuring to see i have normal or below average risks for stuff like heart disease, high blood pressure, type 2 diabetes, several types of cancer, arthritis.
Erica W
Nucleus confirmed the knowledge I already have about my family history, but I also found out that I'm at elevated risk for coronary artery disease, insomnia, and multiple sclerosis.
Maxx Y
I discovered I was at a very high risk for a condition I’d never even heard of—Hereditary Hemochromatosis—which would ultimately change my life.
Ethan C
As the father of two girls (and son of a mom who had breast cancer), I'm grateful to know about my disease risks so we can plan better as a family.
Alexis O
The process couldn’t have been more straightforward. No blood draws…no Dr. visits…just a quick swab of my cheeks.
Jeffrey B
I got the results! I am actually quite impressed. . . the most accurate test I've taken.
Johnny S
Got my results yesterday. Pretty amazing insights, especially one in particular that I wasn’t even aware could be related to genomics and had a deep impact on my life: alcohol.
Gabriel V
Nucleus highlights factors like age, BMI, or cholesterol that are likely to tilt the scales in certain cases. I now plan to have more regular eye exams because my risk for macular degeneration is more strongly correlated with age than I knew.
Michael Hendricks
Invest in your future.
What could cost you thousands is $399.
What could cost you thousands is $399.
Most Popular
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2 kits (for you and yours)
check
2 whole-genome tests
check
Sync partner results
$798
$998
+2 $39/yr memberships
radio_button_unchecked
1 kit
check
1 whole-genome test
$399
$499
+$39/yr membership
check
Free shipping
check
Cancel anytime
Most Popular
radio_button_checked
2 kits (for you + yours)
check
2 whole-genome tests
check
Sync partner results
$798
$998
+$39/yr
radio_button_unchecked
1 kit
check
1 whole-genome test
$399
$499
+$39/yr
check
Free shipping
check
Cancel anytime
Most Popular
radio_button_checked
2 kits (for you + yours)
check
2 whole-genome tests
check
Sync partner results
$798
$998
+$39/yr
radio_button_unchecked
1 kit
check
1 whole-genome test
$399
$499
+$39/yr
check
Free shipping
check
Cancel anytime
How it works
1
Test at home
Testing at home is easy — simply swab your cheek to collect your genetic sample.
2
Send to the lab
"I like being a freelancer because you get to work on diverse projects. It’s learning about different subjects that I really enjoy."
3
Get your results
"I like being a freelancer because you get to work on diverse projects. It’s learning about different subjects that I really enjoy."
1
Test at home
Testing at home is easy — simply swab your cheek to collect your genetic sample.
2
Send to the lab
"I like being a freelancer because you get to work on diverse projects. It’s learning about different subjects that I really enjoy."
3
Get your results
"I like being a freelancer because you get to work on diverse projects. It’s learning about different subjects that I really enjoy."
1
Test at home
Testing at home is easy — simply swab your cheek to collect your genetic sample.
2
Send to the lab
"I like being a freelancer because you get to work on diverse projects. It’s learning about different subjects that I really enjoy."
3
Get your results
"I like being a freelancer because you get to work on diverse projects. It’s learning about different subjects that I really enjoy."
“This $400 genetic test
could save your life.”
“This $400 genetic test could save your life.”
Kristin Houser
Freethink
Understand your risks
Understand your risks
See how your genetics contribute to your health, personality, and longevity.
See how your genetics contribute to your health, personality, and longevity.
Get actionable guidance
Get actionable guidance
Explore choices, make a plan, and improve your health with recommendations designed for you.
Explore choices, make a plan, and improve your health with recommendations designed for you.
Protect your data
HIPAA
HIPAA
COMPLIANT
CLIA
CLIA
CERTIFIED
CAP
CAP
ACCREDITED
check
Clinical-grade security
check
Clinical-grade security
check
Clinical-grade security
check
100% sequenced in the U.S.
check
100% sequenced in the U.S.
check
100% sequenced in the U.S.
check
Sample destroyed after test
check
Sample destroyed after test
check
Sample destroyed after test
For the curious
What will my results tell me?
add
Your Nucleus results include personalized insights about how your unique DNA combines with your lifestyle factors to influence your disease risks and trait dispositions.
Nucleus Premium currently provides reports for the following diseases:
ADHD
Age-related macular degeneration (AMD)
Alcohol dependence
Alzheimer's disease
Anxiety disorders
Asthma
Bipolar disorder
Celiac disease
Chronic pain
Colorectal cancer
Coronary artery disease
Depression
Endometriosis
Female breast cancer
Gastric cancer
Hypertension
Insomnia
Male breast cancer
Migraine
Multiple sclerosis
OCD
Osteoarthritis
Ovarian cancer
Parkinson's disease
Polycystic ovarian syndrome (PCOS)
Prostate cancer
Restless legs syndrome
Rheumatoid arthritis
Schizophrenia
Type 2 diabetes
Nucleus Premium currently provides reports for the following traits:
BMI
Height
IQ
Left-Handedness
Longevity
Male-pattern baldness
Muscle strength
Risk-Taking
Seasonal Allergies
Severe Acne
How is Nucleus different than 23andMe?
add
Most genetic tests look at only a tiny fraction of your DNA — less than 0.1%. This means critical health insights are missed.
That’s why Nucleus sequences your entire genome — all 6 billion letters — so you can mitigate more diseases, make healthier decisions, and live with confidence.
How accurate is Nucleus?
add
Our whole-genome DNA sequencing is more than 99.9% accurate. From research to testing, we go above and beyond industry standards to bring you safe and accurate results.
While your DNA doesn’t change (it’s yours for life!), your Nucleus results can. Genetic research is always improving, so we constantly update your health results to give you the most accurate read on your health.
How do I get my results and how long does it take?
add
Once you place your order, you’ll receive an email from Nucleus with order details and shipping information.
Once you receive your DNA test kit, you’ll be able to take your DNA sample — a simple swab of your cheek — in a matter of minutes. As soon as you’re done, you can ship your sample to our lab using our prepaid USPS shipping label.
When your results are ready, you’ll receive an email notification. Log in to Nucleus on your phone or computer to explore your unique health insights.
How does DNA testing work?
add
Nucleus’ whole-genome test analyzes your DNA for millions of variants that can impact your disease risks. The variants are then classified and interpreted using a combination of new genetic analysis models, public and private databases, and variant interpretation guidelines from nationally recognized genetics associations, such as the American College of Medical Genetics.
Why is there a membership fee?
add
Genetic research is always improving, and we’re committed to keeping you in the know. Your membership gives you updated reports and insights that are at the cutting-edge of genetic research.
Can I download my data?
add
Yes, you can download your DNA file anytime from your Account Settings page. To download your DNA file, go to your Account Settings page and submit a request. You’ll receive an email with your DNA file.
Is Nucleus covered by my insurance?
add
Currently, we do not accept insurance. However, Nucleus is HSA/FSA eligible.
What will my results tell me?
add
Your Nucleus results include personalized insights about how your unique DNA combines with your lifestyle factors to influence your disease risks and trait dispositions.
Nucleus Premium currently provides reports for the following diseases:
ADHD
Age-related macular degeneration (AMD)
Alcohol dependence
Alzheimer's disease
Anxiety disorders
Asthma
Bipolar disorder
Celiac disease
Chronic pain
Colorectal cancer
Coronary artery disease
Depression
Endometriosis
Female breast cancer
Gastric cancer
Hypertension
Insomnia
Male breast cancer
Migraine
Multiple sclerosis
OCD
Osteoarthritis
Ovarian cancer
Parkinson's disease
Polycystic ovarian syndrome (PCOS)
Prostate cancer
Restless legs syndrome
Rheumatoid arthritis
Schizophrenia
Type 2 diabetes
Nucleus Premium currently provides reports for the following traits:
BMI
Height
IQ
Left-Handedness
Longevity
Male-pattern baldness
Muscle strength
Risk-Taking
Seasonal Allergies
Severe Acne
How is Nucleus different than 23andMe?
add
Most genetic tests look at only a tiny fraction of your DNA — less than 0.1%. This means critical health insights are missed.
That’s why Nucleus sequences your entire genome — all 6 billion letters — so you can mitigate more diseases, make healthier decisions, and live with confidence.
How accurate is Nucleus?
add
Our whole-genome DNA sequencing is more than 99.9% accurate. From research to testing, we go above and beyond industry standards to bring you safe and accurate results.
While your DNA doesn’t change (it’s yours for life!), your Nucleus results can. Genetic research is always improving, so we constantly update your health results to give you the most accurate read on your health.
How do I get my results and how long does it take?
add
Once you place your order, you’ll receive an email from Nucleus with order details and shipping information.
Once you receive your DNA test kit, you’ll be able to take your DNA sample — a simple swab of your cheek — in a matter of minutes. As soon as you’re done, you can ship your sample to our lab using our prepaid USPS shipping label.
When your results are ready, you’ll receive an email notification. Log in to Nucleus on your phone or computer to explore your unique health insights.
How does DNA testing work?
add
Nucleus’ whole-genome test analyzes your DNA for millions of variants that can impact your disease risks. The variants are then classified and interpreted using a combination of new genetic analysis models, public and private databases, and variant interpretation guidelines from nationally recognized genetics associations, such as the American College of Medical Genetics.
Why is there a membership fee?
add
Genetic research is always improving, and we’re committed to keeping you in the know. Your membership gives you updated reports and insights that are at the cutting-edge of genetic research.
Can I download my data?
add
Yes, you can download your DNA file anytime from your Account Settings page. To download your DNA file, go to your Account Settings page and submit a request. You’ll receive an email with your DNA file.
Is Nucleus covered by my insurance?
add
Currently, we do not accept insurance. However, Nucleus is HSA/FSA eligible.
What will my results tell me?
add
Your Nucleus results include personalized insights about how your unique DNA combines with your lifestyle factors to influence your disease risks and trait dispositions.
Nucleus Premium currently provides reports for the following diseases:
ADHD
Age-related macular degeneration (AMD)
Alcohol dependence
Alzheimer's disease
Anxiety disorders
Asthma
Bipolar disorder
Celiac disease
Chronic pain
Colorectal cancer
Coronary artery disease
Depression
Endometriosis
Female breast cancer
Gastric cancer
Hypertension
Insomnia
Male breast cancer
Migraine
Multiple sclerosis
OCD
Osteoarthritis
Ovarian cancer
Parkinson's disease
Polycystic ovarian syndrome (PCOS)
Prostate cancer
Restless legs syndrome
Rheumatoid arthritis
Schizophrenia
Type 2 diabetes
Nucleus Premium currently provides reports for the following traits:
BMI
Height
IQ
Left-Handedness
Longevity
Male-pattern baldness
Muscle strength
Risk-Taking
Seasonal Allergies
Severe Acne
How is Nucleus different than 23andMe?
add
Most genetic tests look at only a tiny fraction of your DNA — less than 0.1%. This means critical health insights are missed.
That’s why Nucleus sequences your entire genome — all 6 billion letters — so you can mitigate more diseases, make healthier decisions, and live with confidence.
How accurate is Nucleus?
add
Our whole-genome DNA sequencing is more than 99.9% accurate. From research to testing, we go above and beyond industry standards to bring you safe and accurate results.
While your DNA doesn’t change (it’s yours for life!), your Nucleus results can. Genetic research is always improving, so we constantly update your health results to give you the most accurate read on your health.
How do I get my results and how long does it take?
add
Once you place your order, you’ll receive an email from Nucleus with order details and shipping information.
Once you receive your DNA test kit, you’ll be able to take your DNA sample — a simple swab of your cheek — in a matter of minutes. As soon as you’re done, you can ship your sample to our lab using our prepaid USPS shipping label.
When your results are ready, you’ll receive an email notification. Log in to Nucleus on your phone or computer to explore your unique health insights.
How does DNA testing work?
add
Nucleus’ whole-genome test analyzes your DNA for millions of variants that can impact your disease risks. The variants are then classified and interpreted using a combination of new genetic analysis models, public and private databases, and variant interpretation guidelines from nationally recognized genetics associations, such as the American College of Medical Genetics.
Why is there a membership fee?
add
Genetic research is always improving, and we’re committed to keeping you in the know. Your membership gives you updated reports and insights that are at the cutting-edge of genetic research.
Can I download my data?
add
Yes, you can download your DNA file anytime from your Account Settings page. To download your DNA file, go to your Account Settings page and submit a request. You’ll receive an email with your DNA file.
Is Nucleus covered by my insurance?
add
Currently, we do not accept insurance. However, Nucleus is HSA/FSA eligible.
Top resources
GenePlaza review: Everything you need to know
GeneDx Reviews: How reliable are their exome and genome testing services?
Natera Horizon vs. Panorama: How do these DNA tests differ?
Natera vs. Myriad: How do these genetic testing services measure up?
Natera genetic testing reviews: Learn all about its tests, accuracy, and pricing
Ambry Genetics reviews: Key facts to know before testing
Top resources
GenePlaza review: Everything you need to know
GeneDx Reviews: How reliable are their exome and genome testing services?
Natera Horizon vs. Panorama: How do these DNA tests differ?
Natera vs. Myriad: How do these genetic testing services measure up?
Natera genetic testing reviews: Learn all about its tests, accuracy, and pricing
Ambry Genetics reviews: Key facts to know before testing
Top resources
GenePlaza review: Everything you need to know
GeneDx Reviews: How reliable are their exome and genome testing services?
Natera Horizon vs. Panorama: How do these DNA tests differ?
Natera vs. Myriad: How do these genetic testing services measure up?
Natera genetic testing reviews: Learn all about its tests, accuracy, and pricing
Ambry Genetics reviews: Key facts to know before testing
Learn
HIPAA-COMPLIANT
CLIA-CERTIFIED
CAP-accredited
Made in the U.S.A.
© 2025 Nucleus Genomics, Inc.
Learn
© 2025 Nucleus Genomics, Inc.
HIPAA-COMPLIANT
CLIA-CERTIFIED
CAP-accredited
Made in the U.S.A.
Learn
HIPAA-COMPLIANT
CLIA-CERTIFIED
CAP-accredited
Made in the U.S.A.
© 2025 Nucleus Genomics, Inc.