We've had a breakthrough in applying AI to genetic analysis.
Origin is a family of nine genetic optimization models that predict human longevity from an embryo’s DNA more accurately than any genetic model to date.
Trained and validated on data from millions of individuals, Origin sets new accuracy benchmarks for predicting age-related conditions such as heart disease and cancers across diverse ancestries.
Developed by Nucleus Labs, our research arm, Origin reflects a commitment to both scientific rigor and transparency. Origin’s full model weights will be publicly available, allowing patients, providers, and researchers to see how the models work, evaluate their performance, and build upon them.
Specifically, the Origin models will be hosted in the Genetic Optimization Hub, a public resource for all companies, laboratories, and academics to publish and compare model accuracy. Each model entry will include information on training and validation data, uncertainty ranges, and performance across ancestries to support clarity and reproducibility.
Until now, Nucleus’ models — like others in the industry — were considered proprietary, making it difficult for providers, parents, and researchers to understand and evaluate them. We’re changing that because we believe the future of genomics should be built in public.
With the open-weighting of Origin, patients can see how genetics can ensure a long and healthy life for themselves and their child. Providers can recognize that genetic optimization is ready for clinical integration. And regulators can see genetic optimization for what it truly is: the ultimate tool for preventative medicine.
For Nucleus, science is only complete when it helps a family. Nucleus is proud that Origin is already in use with our IVF+ partners, reaching patients through leading IVF practitioners in Los Angeles, New York, and Mexico City. All existing Nucleus Family and Health patients will also receive these updates, helping thousands more families around the world.
Together with our IVF and reproductive medicine partners, we’re making genetic innovation available to families everywhere.
To the patients who place their trust in us—thank you. Whether our DNA kits or IVF+, we’re honored to support you in building generational health.
